Nocturnal Hypoxia in Geriatric Patients After Hip Fracture

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala

Ingia / Ingia

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HaliBado kuajiri

Wadhamini

Assistance Publique - Hôpitaux de Paris

JARIBIO LA KLINIKI: NCT04007432

BioSeek: nct04007432

Maneno muhimu

Kikemikali

Delirium is a common complication following hip fracture surgery (HFS) in older people. Postoperative hypoxia has also been associated with delirium, but not specifically in geriatric patients. The aim of the study is to demonstrate that post-operative hypoxia is associated with in-hospital complications in patients with HFS.

Maelezo

Patients hospitalized in orthogeriatric unit after HFS will be monitored for nocturnal SpO2 with a pulse oximeter continuously during 3 nights. In-hospital complications will be recorded prospectively in all patients, especially the occurrence of delirium with the CAM scale. The hypoxia vs non-hypoxia (more than 20% of the time spent with SpO2<90%) groups will be analyzed for clinical characteristics, comorbidities and medication use.

The statistical association between severe post-operative nocturnal hypoxemia and occurrence of delirium will be assessed. The dependance between this association and daytime SpO2 will also be assessed. The potential confirmation of an association between post-operative nocturnal hypoxemia in patients with HFS and the occurrence of delirium will lead the reflection on a clinical trial testing the benefit of oxygen therapy in the prevention of post-operative delirium, to improve the medical care of orthogeriatric patients.

Tarehe

Imethibitishwa Mwisho:	05/31/2019
Iliyowasilishwa Kwanza:	06/17/2019
Uandikishaji uliokadiriwa Uliwasilishwa:	06/30/2019
Iliyotumwa Kwanza:	07/04/2019
Sasisho la Mwisho Liliwasilishwa:	02/16/2020
Sasisho la Mwisho Lilichapishwa:	02/18/2020
Tarehe halisi ya kuanza kwa masomo:	02/29/2020
Tarehe ya Kukamilisha Msingi iliyokadiriwa:	08/31/2021
Tarehe ya Kukamilisha Utafiti:	08/31/2021

Hali au ugonjwa

Delirium

Hypoxia

Uingiliaji / matibabu

Other: Older patients with hip fracture

Awamu

Vikundi vya Arm

Mkono	Uingiliaji / matibabu
Experimental: Older patients with hip fracture Older patients admitted for hip fracture surgery	Other: Older patients with hip fracture Nocturnal oxymetry data will be continuously collected during nighttime by a pulse oxymeter, covering for 1 to 3 nights.

Vigezo vya Kustahiki

Zama zinazostahiki Kujifunza	70 Years Kwa 70 Years
Jinsia Inastahiki Kujifunza	All
Hupokea Wajitolea wa Afya	Ndio
Vigezo	Inclusion Criteria: - age over 70 years old, - hospitalized in orthogeriatrics for hip fracture surgery - information about the study and expression of non opposition Exclusion Criteria: - patient under guardianship, - any other type of fracture associated, - oxymetry recording not possible (behavioral disorders, night stirring,...)

Matokeo

Hatua za Matokeo ya Msingi

1. Delirium [Month 1]

Delirum or not, diagnosed with CAM (Confusion Assessment Method). Association between nocturnal hypoxia and delirium will be study.

Hatua za Matokeo ya Sekondari

1. In-hospital complications [Month 1]

Occurrence of in-hospital complications (infection, cardiac, etc). Association between nocturnal hypoxia and others medical complications (infection, cardiac, etc) will be study.

2. Length of hospitalisation stay in othogeriatrics unit [Month 1]

Length of stay in othogeriatrics unit. Association between nocturnal hypoxia and length of hospitalisation stay in othogeriatrics unit will be study.

3. walking status (functional status) [Month 1]

walking status (possible with/without help, wheelchair or bedridden) Association between nocturnal hypoxia and functional status will be study.

4. walking status (functional status) [Month 6]

walking status (possible with/without help, wheelchair or bedridden). Association between nocturnal hypoxia and functional status will be study.

5. walking speed (functional status) [Month 1]

walking speed for 5 meter. Association between nocturnal hypoxia and functional status will be study.

6. walking speed (functional status) [Month 6]

walking speed for 5 meter. Association between nocturnal hypoxia and functional status will be study.

7. Physical performance (functional status) [Month 1]

Short Physical Performance Battery (SPPB) is an objective assessment tool for evaluating lower extremity functioning in older persons.

8. Physical performance (functional status) [Month 6]

Short Physical Performance Battery (SPPB) is an objective assessment tool for evaluating lower extremity functioning in older persons.

9. Dependency [Month 1]

Activities of Daily Living (ADL) and Instrumental Activities of Daily Living (IADL) are instrument to assess independent living skills. Association between nocturnal hypoxia and independent living skills will be study.

10. Dependency [Month 6]

11. Mortality [Month 1]

Vital status will be raised

12. Mortality [Month 6]