Polyunsaturated Fatty Acids in Child Nutrition
Maneno muhimu
Kikemikali
Maelezo
A well balanced supply of polyunsaturated fatty acids, in particular the omega-3 long chain docosahexaenoic acid (DHA), in early childhood is essential for children's cognitive and visual development. DHA can either be supplied preformed in the diet (e.g. via fatty fish) or synthesised by conversion of its essential precursor alpha-linolenic acid (e.g. via rapeseed oil). The study examines the effect of two different approaches to optimise infants´ fatty acid status.
The study sample consists of healthy newborns and their mothers (3 x 57 infants according to a priori power calculation) who are enrolled in delivery hospitals in the region of Dortmund, Germany. In total, the individual study program covers the first 10 months of infant's life. Biomarkers of fatty acid status from the mother are collected 8 weeks pp for the estimation of pre- and perinatal fatty acid supply. Additionally, information on maternal diet during pregnancy and after delivery is assessed. The intervention covers the period of complementary feeding (from 4 to 6 months of age until 10 months of age). In all groups the specific study food is given 5 to 7 times a week, whereas 2 of these are fish meals in the fatty fish group. At the age of 4 and 10 months blood samples are collected from the infants to examine the effect on blood fatty acid status. Parameters of visual and cognitive development are also assessed at the age of 4 and 10 months using VEP examinations and Bayley scales. Infants´ dietary intake is assessed from the end of the 2 months until 10 months of age using continuous weighed dietary records.
Tarehe
| Imethibitishwa Mwisho: | 10/31/2014 |
| Iliyowasilishwa Kwanza: | 09/14/2011 |
| Uandikishaji uliokadiriwa Uliwasilishwa: | 12/05/2011 |
| Iliyotumwa Kwanza: | 12/07/2011 |
| Sasisho la Mwisho Liliwasilishwa: | 11/04/2014 |
| Sasisho la Mwisho Lilichapishwa: | 11/05/2014 |
| Tarehe halisi ya kuanza kwa masomo: | 03/31/2011 |
| Tarehe ya Kukamilisha Msingi iliyokadiriwa: | 08/31/2013 |
| Tarehe ya Kukamilisha Utafiti: | 08/31/2013 |
Hali au ugonjwa
Uingiliaji / matibabu
Other: Fatty acid composition of complementary food
Awamu
Vikundi vya Arm
| Mkono | Uingiliaji / matibabu |
|---|---|
| Experimental: Rapeseed oil Study group receive commercial vegetable-potato-meat-meals containing rapeseed oil as part of complementary food | |
| Experimental: Fatty fish Study group receive 2 times per week a vegetable-potato-meat-meals as part of complementary food. | |
| Active Comparator: Corn oil Study group receive commercial vegetable-potato-meat-meals containing corn oil as part of complementary food |
Vigezo vya Kustahiki
| Jinsia Inastahiki Kujifunza | All |
| Hupokea Wajitolea wa Afya | Ndio |
| Vigezo | Inclusion Criteria: - a term healthy newborn infant ( birth weight > 2500 g, gestational age > 37 weeks - German speaking mother - the intention of the mother to breast-feed the children and to feed study menus at least 5 times per week beginning in the fifth to seventh month of life. Exclusion Criteria: - preterm children - twins |
Matokeo
Hatua za Matokeo ya Msingi
1. Infants´ fatty acid status [10 months after delivery]
Hatua za Matokeo ya Sekondari
1. Infants´ visual development [10 months after delivery]
2. Infants´ cognitive development [10 months after delivery]
3. Infants´ haemogram [10 months after delivery]
4. Infants´antioxidant status [10 months after delivery]
5. Infants´ body weight [10 months after delivery]
6. Infants´ dietary intake [from 2 until 10 months after delivery]
7. Maternal dietary intake [pregnancy and first 2 months post partum]
8. Infant's preference for fish [10 month after delivery]
9. Infant's preference for new flavour [10 month after delivery]
10. Parental attitudes about fish and feeding strategies [10 months after delivery]
11. Mother´s fatty acid status [2 months after delivery]
12. Infants´ body length [10 months after delivery]
13. Infant´s head circumference [10 months after delivery]
