RiSE to Prevent Cardiovascular Disease in African Americans
Maneno muhimu
Kikemikali
Maelezo
The purpose of this study is to examine an 8-week stress reduction program for African Americans. The aim of this study is to determine the effectiveness of this stress reduction program in improving well-being and reducing risk for heart disease and stroke in African Americans.
No drugs are involved with this study. Participants will be randomized (randomly selected) to either participate in an 8 -week stress reduction program or a control group (no stress reduction program). The stress reduction program entails attending a 2- hour small group class once a week for 8 consecutive weeks at Loyola University in Maywood. Classes will be offered in the evening and will focus on teaching effective strategies for coping with daily stress, particularly stress associated with being an African American.
Blood and saliva samples will be collected at the beginning of the study, in the middle of the program (4 weeks), at the end of the program (8 weeks) and 3 months after the program ends. Blood samples will be analyzed for cholesterol levels, hemoglobin A1c (a measure that reflects blood sugar over time), and cytokines (which reflect inflammation in the body). Saliva samples will be assessed for a hormone called cortisol..
Participants will also complete several written questionnaires to gather information about their stress, social status, perceive discrimination, mood, diet and exercise. Participants will be paid $25 for each of the three data collection time points ($75 total). Those participants who are randomized to attend the stress reduction classes will also be provided $15 for each class that they attend (8 X $15 = $120) to help cover travel expenses.
Tarehe
Imethibitishwa Mwisho: | 09/30/2019 |
Iliyowasilishwa Kwanza: | 03/13/2019 |
Uandikishaji uliokadiriwa Uliwasilishwa: | 03/14/2019 |
Iliyotumwa Kwanza: | 03/17/2019 |
Sasisho la Mwisho Liliwasilishwa: | 10/21/2019 |
Sasisho la Mwisho Lilichapishwa: | 10/22/2019 |
Tarehe halisi ya kuanza kwa masomo: | 08/02/2017 |
Tarehe ya Kukamilisha Msingi iliyokadiriwa: | 06/30/2019 |
Tarehe ya Kukamilisha Utafiti: | 09/30/2019 |
Hali au ugonjwa
Uingiliaji / matibabu
Behavioral: 8-week RiSE
Awamu
Vikundi vya Arm
Mkono | Uingiliaji / matibabu |
---|---|
Experimental: 8-week RiSE Participate in 8-week Resilience, Stress, and Ethnicity (RiSE) group based stress reduction program in which participants meet every week for approximately 2 hours for 8 consecutive weeks. | Behavioral: 8-week RiSE Group based stress reduction program focused on helping minorities develop coping and empowerment skills |
No Intervention: Control Treatment as usual |
Vigezo vya Kustahiki
Zama zinazostahiki Kujifunza | 25 Years Kwa 25 Years |
Jinsia Inastahiki Kujifunza | All |
Hupokea Wajitolea wa Afya | Ndio |
Vigezo | Inclusion Criteria: - African American - Living in Maywood community or surrounding area - Able to speak, read, write English - Have at least one of the following: - Body Mass Index (BMI) > 25 (overweight or obese) - Total cholesterol > 240 - Diabetes mellitus - Systolic blood pressure the same or greater than 120 mmHg or diagnosis of hypertension and/or taking antihypertensive medication - Atrial fibrillation - Parental history of myocardial infarction (MI) (heart attack) prior to age 60 Exclusion Criteria: - Current smoker (smoked in last month) - History of myocardial infarction or ischemic heart disease - Current cancer - Active infection - Major Immune-related disorder (lupus,MS) - Substance abuse - Immune-altering drugs - Recent dental procedure (within past 72 hours - Bleeding gums or periodontal disease |
Matokeo
Hatua za Matokeo ya Msingi
1. Feasibility of RiSE intervention: questionnaire [8 weeks]
2. Coping [8 weeks]
3. Coping with Discrimination [8 weeks]
4. Resilience [8 weeks]
Hatua za Matokeo ya Sekondari
1. Inflammatory burden [8 weeks]