Stem Cells Found in the Abdominal Cavity in Humans
Maneno muhimu
Kikemikali
Maelezo
The purpose of this study is to determine the presence and characterization of stem cells in human peritoneal cavity. Peritoneal lavage fluid from patients who undergo elective open abdomen will be collected for this purpose. Peritoneal lavage is normally a routine part of abdominal surgical procedure and usually is discarded after surgery. The patient will undergo surgical procedure as usual and there will be no added procedures during surgery.
This study will collect and analyze peritoneal fluid for the existence and characteristics of stem cells from 15 patients undergoing scheduled elective intra-abdominal surgery by designated surgeons at Cedars-Sinai Medical Center. The types of abdominal surgery could be open abdominal surgery or laparoscopic surgery. Peritoneal washing is routinely done in abdominal surgeries. We will collect these fluids to analyze whether stem cells exist in human peritoneal cavity. The fluids will be collected in a sterile fashion. The collected fluid will be further processed in the laboratory for the purpose of the study.
Medical record review will be conducted. Information collected will include age, gender, past and current medical history, current indication for intra-abdominal surgery, substance exposure history, medication history which will be obtained from review of patients' medical records. The information will be maintained using coded entry and there will be no link between patient identifiers to the study codes.
Tarehe
Imethibitishwa Mwisho: | 11/30/2007 |
Iliyowasilishwa Kwanza: | 12/17/2007 |
Uandikishaji uliokadiriwa Uliwasilishwa: | 12/17/2007 |
Iliyotumwa Kwanza: | 12/18/2007 |
Sasisho la Mwisho Liliwasilishwa: | 06/23/2011 |
Sasisho la Mwisho Lilichapishwa: | 06/26/2011 |
Tarehe halisi ya kuanza kwa masomo: | 03/31/2007 |
Tarehe ya Kukamilisha Utafiti: | 01/31/2012 |
Hali au ugonjwa
Awamu
Vigezo vya Kustahiki
Zama zinazostahiki Kujifunza | 18 Years Kwa 18 Years |
Jinsia Inastahiki Kujifunza | All |
Njia ya sampuli | Probability Sample |
Hupokea Wajitolea wa Afya | Ndio |
Vigezo | Inclusion Criteria: 1. 20-60 years old 2. Male or females who are scheduled to undergo elective abdomen surgery Exclusion Criteria: 1. Minors 2. Pregnant women 3. Known personal or family history of genetic disorders 4. Known history of malignancy 5. Known history of advanced liver or renal disease 6. HIV Positive: only patients who have tested negative during routine testing of their donated blood prior to surgery will be included in the study. 7. Hepatitis B and C positive 8. Scheduled to undergo lap banding |