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Journal of Asian Natural Products Research 2016-Aug

A potent antibacterial indole alkaloid from Psychotria pilifera.

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
Kiungo kimehifadhiwa kwenye clipboard
Lu Liu
Chang-Wei Song
Afsar Khan
Xiao-Ning Li
Xing-Wei Yang
Gui-Guang Cheng
Ya-Ping Liu
Xiao-Dong Luo

Maneno muhimu

Kikemikali

A new strychnine alkaloid, 16,17,19,20-tetrahydro-2,16-dehydro-18-deoxyisostrychnine (1), and fourteen known alkaloids were isolated from the leaves of Psychotria pilifera. Their structures were identified on the basis of extensive spectroscopic analysis, as well as by comparison with the reported spectroscopic data. The new alkaloid (1) exhibited potent antibacterial activity against Escherichia coli, equivalent to cefotaxime with MIC value of 0.781 μg/ml.

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