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Planta Medica 2008-Feb

Anti-allergic prenylated flavonoids from the roots of Sophora flavescens.

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
Kiungo kimehifadhiwa kwenye clipboard
Wenying Quan
Hee Ju Lee
Chul Young Kim
Chu Won Noh
Byung Hun Um
Min-Ho Oak
Kyeong-Man Kim

Maneno muhimu

Kikemikali

The bioassay-guided fractionation of the MeOH extract from the root of Sophora flavescens led to the isolation of eight known prenylated flavonoids ( 1 - 8) responsible for the IN VITRO anti-allergic activity. Among them, kushenol N ( 3), sophoraflavanone G ( 6), and leachianone A ( 7) demonstrated significant inhibition of the release of beta-hexosaminidase from cultured RBL-2H3 cells with IC (50) values ranging from 15 to 30 muM.

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