Journal of Natural Products 2012-Mar

Chlorinated englerins with selective inhibition of renal cancer cell growth.

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala

Ingia / Ingia

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Rhone K Akee

Tanya Ransom

Ranjala Ratnayake

James B McMahon

John A Beutler

KIFUNGU: 22280462

DOI: 10.1021/np200905u

PMC: PMC3311709

BioSeek: 22280462

Maneno muhimu

Kikemikali

The chlorinated englerins (3-9) were isolated from Phyllanthus engleri and shown to selectively inhibit the growth of renal cancer cells. The compounds were shown to be extraction artifacts produced by exposure to chloroform decomposition products during their isolation. The most active compound, 3, was synthesized from englerin A (1).

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Herbal & Natural Medicine

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Chlorinated englerins with selective inhibition of renal cancer cell growth.

Maneno muhimu

kidney neoplasms

saratani

chloroform

phyllanthus

phyllanthus engleri

Kikemikali

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