Zeitschrift für Naturforschung - Section C Journal of Biosciences

Cytotoxic rocaglamide derivatives from Aglaia duppereana.

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala

Ingia / Ingia

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Mona El-Neketi

Weaam Ebrahim

Ngoc Tu Duong

Sahar Gedara

Farid Badria

Hassan-Elrady A Saad

Werner E G Müller

Peter Proksch

KIFUNGU: 24066511

BioSeek: 24066511

Maneno muhimu

Kikemikali

Phytochemical investigation of Aglaia duppereana flowers led to the isolation of a new rocaglamide derivative and twelve known congeners. The structure of the new compound was unambiguously elucidated by spectroscopic techniques (1D- and 2D-NMR, HRESIMS). The isolated compounds exhibited a potent cytotoxic activity against mouse lymphoma (L5178Y) cells with EC50 values ranging from 5.1 to 54.8 nM.

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Herbal & Natural Medicine

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Cytotoxic rocaglamide derivatives from Aglaia duppereana.

Maneno muhimu

rocaglamide

aglaia

lymphoma

Kikemikali

Hifadhidata kamili ya mimea ya dawa inayoungwa mkono na sayansi