Journal of Natural Products 2007-Aug

Leuconoxine, kopsinitarine, kopsijasmine, and kopsinone derivatives from Kopsia.

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala

Ingia / Ingia

Kiungo kimehifadhiwa kwenye clipboard

Siew-Huah Lim

Kooi-Mow Sim

Zanariah Abdullah

Osamu Hiraku

Masahiko Hayashi

Kanki Komiyama

Toh-Seok Kam

KIFUNGU: 17608533

DOI: 10.1021/np0701778

BioSeek: 17608533

Maneno muhimu

Kikemikali

Four new indole alkaloids were obtained from two Kopsia species, 6-oxoleuconoxine (1) from the leaf extract of K. griffithii and kopsinitarine E (2), kopsijasminine (3), and kopsonoline (4) from the stem-bark extract of K. teoi. The structures of these alkaloids were determined using NMR and MS analysis. Kopsijasminine (3) showed moderate activity in reversing multidrug resistance in vincristine-resistant KB cells.

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Herbal & Natural Medicine

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Leuconoxine, kopsinitarine, kopsijasmine, and kopsinone derivatives from Kopsia.

Maneno muhimu

vincristine

alkaloid

indole

kopsia

Kikemikali

Hifadhidata kamili ya mimea ya dawa inayoungwa mkono na sayansi