Journal of Enzyme Inhibition and Medicinal Chemistry 2008-Feb

Lipoxygenase inhibiting and antioxidant iridoids from Buddleja crispa.

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Ingia / Ingia

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Ijaz Ahmad

Shilin Chen

Yong Peng

Sibao Chen

Lijia Xu

KIFUNGU: 18341266

DOI: 10.1080/14756360701342532

BioSeek: 18341266

Maneno muhimu

Kikemikali

Phytochemical investigations on the ethyl acetate-soluble fraction of the whole plant of Buddleja crispa led to the isolation of the iridoids 1-7. Compound 2 displayed significant inhibitory potential against enzyme lipoxygenase in a concentration-dependant fashion with IC(50) value of 39.7 +/- 0.02microM, along with DPPH radical scavenging activity with IC(50) value 0.638 mM.

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Herbal & Natural Medicine

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Lipoxygenase inhibiting and antioxidant iridoids from Buddleja crispa.

Maneno muhimu

lipoxygenase

ethyl acetate

iridoid

buddleja crispa

buddleja

antioxidant

Kikemikali

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