Arzneimittel-Forschung 1994-Sep

New 4-arylaminopiperidines with antihypoxic and anticonvulsive activity.

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala

Ingia / Ingia

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G Domány

G Barta-Szalai

E Pálosi

S Szabó

I Schön

KIFUNGU: 7986252

BioSeek: 7986252

Maneno muhimu

Kikemikali

Several new bioanalogues of (+/-)-N-methyl-N-(1-[3-(4-fluorophenoxy)-2-hydroxy-propyl]piperidin++ +-4-yl) benzothiazol-2-amine (1, sabeluzole, CAS 104383-17-7) were prepared by reacting 1,2-epoxy-3-aryloxypropanes with 4-arylaminopiperidines. Some of these derivatives showed enhanced activity in the potassium cyanide hypoxia test and in the pentetrazol convulsion test in mice compared to 1.

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Herbal & Natural Medicine

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New 4-arylaminopiperidines with antihypoxic and anticonvulsive activity.

Maneno muhimu

cyanide

kali

hypoxia

seizures

benzothiazol

Kikemikali

Hifadhidata kamili ya mimea ya dawa inayoungwa mkono na sayansi