[Ophthalmology].

Allergic conjunctival diseases caused by immediate hypersensitivity are classified into several subtypes, including seasonal or perennial allergic conjunctivitis, vernal keratoconjunctivitis (VKC), atopic karatoconjunctivitis, giant papillary conjunctivitis. The gold standard in treatment of seasonal allergic conjunctivitis, especially Japanese cedar pollinosis, is anti allergic ophthalmic solution, mast cell stabilizer and histamine H1 blocker. During the peak pollen count period, we use an ophthalmic steroid solution. Preseasonal treatment with anti allergic ophthalmic solution is effective to decrease symptoms during the peak pollen count period. Topical steroids are most effective treatment for VKC, but are also frequently associated with increasing intraocular pressure. A recent treatment combining anti allergic ophthalmic solution, steroid ophthalmic solution and topical immunomodulator (cyclosporine 0.1% or tacrolimus 0.1%) proves very effective and safe for severe VKC.