Natural Product Communications 2014-Oct

Two new alkaloids from Melodinus suaveolens.

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala

Ingia / Ingia

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Fan Lu

Pan Liu

Shan-Shan Yin

Jun Zhang

Jing Wang

KIFUNGU: 25522534

BioSeek: 25522534

Maneno muhimu

Kikemikali

Two new Melodinus-type alkaloids, 15β-hydroxy-14,15-dihydroscandine (1) and 14,15-dihydroscandine (2), together with 6 known ones were isolated from Melodinus suaveolens. The structures of the new compounds were identified from spectroscopic (NMR, UV, IR, CD) and mass spectrometric data and Mosher's method. The new compounds exhibited significant, dose-dependent inhibition of the production of lipopolysaccharide (LPS)-induced NO, IL-6 and IL-8 in mice macrophages.

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Herbal & Natural Medicine

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Two new alkaloids from Melodinus suaveolens.

Maneno muhimu

alkaloid

melodinus

melodinus suaveolens

Kikemikali

Hifadhidata kamili ya mimea ya dawa inayoungwa mkono na sayansi