african/antioxidant

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Effect of Resveratrol on Serum IGF2 Among African American Women

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Ingia / Ingia

Resveratrol (RSV) is a naturally occurring polyphenol found in many plants including grapes, peanuts and berries. Resveratrol has attracted a lot of research attention based on preclinical data showing anti-inflammatory and anti-oxidative properties through several mechanisms.RSV is available as

Effects of Herbal Antioxidants on Cardiovascular Disease in Older Blacks

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Ingia / Ingia

Older African Americans suffer from disproportionately high rates of cardiovascular disease (CVD) morbidity and mortality. In response to the health disparity between older African Americans and whites, national mandates have called for new research on innovative approaches to CVD prevention in this

The Effect of Antioxidants on Skin Blood Flow During Local Heating

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Ingia / Ingia

The integrative vascular laboratory has recently observed that the small blood vessels in the skin (the cutaneous microvasculature) in obese (BMI>30kg/m2), but otherwise healthy individuals, require a greater amount of nitric oxide (NO) to achieve the same degree of dilation when compared to age,

Racial and Aging Effects of Acute Antioxidant Supplementation

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Ingia / Ingia

The overall goal of this application is to investigate the effect of aging on how acute antioxidant supplementation affects decrements in arterial function observed in African Americans (AA). Additionally, this application will facilitate the applicant's emergence as an independent investigator in

The Effect of Antioxidants on Skin Blood Flow-BH4

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Ingia / Ingia

African Americans (AA) not only have a higher prevalence of hypertension but the severity of the cardiovascular complications related to this condition are greater in this population relative to other populations. While the underlying causes of this elevated risk are multifactorial, vascular

The Effect of Local Antioxidant Therapy on Racial Differences in Vasoconstriction

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Ingia / Ingia

Cardiovascular disease (CVD) afflicts nearly one-third of the adult population with all races and ethnicities represented in CVD prevalence. Unfortunately, a disparity exists such that the black population (BL) is disproportionately affected compared to other groups, including the white population

Vitamin E and C to Slow Progression of Common Carotid Artery Plaque Build-Up

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Ingia / Ingia

BACKGROUND: Evidence from epidemiologic studies, and from one unpublished study, suggests that greater intake of antioxidant vitamins is associated with reduced risk of coronary heart disease and stroke. Findings from an animal model indicate that increased intake of antioxidant vitamins prevents

Green Tea Extract: a Non-Surgical Alternative for Treatment of Uterine Fibroids

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Ingia / Ingia

- Uterine leiomyoma (also known as fibroids) are benign estrogen-dependent tumors of the uterine wall. Uterine fibroids are the most common tumors of the female reproductive tract, occurring in 20-70% of premenopausal women in the reproductive age women and cause multiple clinical complications such

Soy Protein in Preventing Recurrent Cancer in Patients Who Have Undergone Surgery for Stage II Prostate Cancer

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Ingia / Ingia

OBJECTIVES: - Determine whether soy protein isolate reduces the PSA failure rate and time to PSA failure within 2 years following radical prostatectomy in patients who are at high risk for prostate cancer recurrence. - Determine the effects of soy protein isolate on intermediate biomarkers of

Moringa Oleifera- Antiretroviral Pharmacokinetic Drug Interaction

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Ingia / Ingia

The use of herbal supplements is widespread in Africa, particularly for the management of HIV and AIDS. In Zimbabwe, the prevalence of herbal medicine use in HIV-infected people is as high as 79% (Sebit et al., 2000). Several studies have shown that the herb Moringa oleifera is among the top 10

Effect of MitoQ on Platelet Function and Reactive Oxygen Species Generation in Patients With Sickle Cell Anemia

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Ingia / Ingia

Antioxidant therapies targeted to specific enzymes or compartments may be beneficial in sickle cell anemia (SCA). MitoQ, the most extensively studied mitochondrial-targeted antioxidant, has been shown to be protective against ischemia/reperfusion injury in the heart, endothelial damage due to

Meat-based Versus Pesco-vegetarian Diet and Colorectal Cancer

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Ingia / Ingia

Colorectal cancer (CRC) is the second leading cause of cancer death in Europe. The geographical variation of incidence demonstrates how environmental factors, chiefly dietary habits, play a major role in this disease. Convincing evidence suggests that risk of CRC is increased by red meat and

The Efficacy of Jobelyn (Sorghum Bicolor Extract)in the Treatment of Sickle Cell Anemia

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Ingia / Ingia

Sickle cell anaemia is an inherited haemoglobinopathy caused by a point missense mutation (GAG to GTG) in the beta globin gene that resulted in the substitution of an acidic amino acid ( glutamic acid) with a neutral and hydrophobic amino acid (valine) in the codon 6 of the beta globin chain. This

Serum, Dietary and Supplemental Vitamin D's Association With Cognitive Decline

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Ingia / Ingia

INTRODUCTION Cognitive impairment, a principal cause for functional disability among the elderly, can lead to dementing illness over time mainly in the forms of Alzheimer's Disease (AD) and vascular dementia (VaD). In fact, AD prevalence is expected to rise, reaching 100 million worldwide by 2050,

Effect of Saxagliptin and Dapagliflozin on Endothelial Progenitor Cell in Patients With Type 2 Diabetes Mellitus

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Ingia / Ingia

The Investigator hypothesize that Dapagliflozin will improve EPC number and function AND Saxagliptin in addition to Dapagliflozin may have an additive effect to improve EPC number and function even more than Dapa alone, compared to placebo. In this proposal the investigator plan to conduct a placebo

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