african/atrophy

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Ukurasa 1 kutoka 32 matokeo

The African-PREDICT Study

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Ingia / Ingia

Background and Problem Statement: Recent global analyses have indicated that the highest blood pressures worldwide are recorded in black populations. The vulnerable cardiovascular profile of Africans is believed to result from a combination of factors such as rapid urbanisation, abnormal sodium

Rosuvastatin in African Americans With Cerebrovascular Disease

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Ingia / Ingia

Background: Blacks have twice the risk of stroke compared to Whites and a recent analysis found that stroke incidence was decreasing in Whites but not Blacks. Identifying new avenues for stroke prevention is important in African Americans. The Stroke Prevention through Aggressive Reduction of

African American Alzheimer's Progression Markers - CSF and Neuro-Imaging

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Ingia / Ingia

African Americans represent about 10% of the population in the US, but are under-represented in biomarker-related aging studies such as the Alzheimer's Disease Neuro-imaging Initiative (ADNI) and World Wide ADNI. Epidemiologic studies show that, compared to non-Hispanic white (NHW) Americans,

Detroit Young Adult Asthma Project

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Ingia / Ingia

Racial and ethnic minority youth have poorer asthma status than Caucasian youth, even after controlling for socioeconomic variables. Proper use of asthma controller medications is critical in reducing asthma mortality and morbidity. The clinical consequences of poor asthma management include

The Exercise, Arterial Modulation and Nutrition in Youth South Africa Study

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Ingia / Ingia

Background: The current global widespread incidence of obesity and early cardiovascular deterioration are two of the most important future health care challenges. Physical inactivity and its associated unhealthy dietary intake among adolescents are of great concern, especially in a South African

Mindfulness Attitude to Deliver Dietary Approach to Stop Hypertension

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Ingia / Ingia

Hypertension (HTN), known as the "silent killer" affects 1 in 3 adults in the United States at a cost of $50 billion annually and disproportionately affects African Americans (AA). A significant proportion of the AA population is living with blood pressures consistent with the clinical criteria for

Ranibizumab for Neovascularization in Sickle Cell Retinopathy

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Ingia / Ingia

In the U.S., about 10% of African Americans have an abnormal hemoglobin gene. About 8% of African Americans are heterozygous for Hemoglobin S. In the United States, sickle cell anemia primarily occurs in the black population, with approximately 0.2% of African American children afflicted by this

Muscle Stimulation for Physical Function During Stem Cell Transplant

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Ingia / Ingia

Hematopoietic cell transplantation (HCT) reduces physical function and muscle mass and increases fatigue. Neuromuscular electrical stimulation (NMES), when used as a stand-alone intervention, improves muscle strength and muscle mass in non-cancer patients with chronic obstructive pulmonary disease

Genes, Exercise, Neurocognitive and Neurodegeneration: Community-Based Approach

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Ingia / Ingia

Although anticholinesterase therapies have greatly improved the symptomatic treatment of Alzheimer's disease (AD), they have not been demonstrated to significantly slow the disease progression; and amyloid-directed therapies have produced disappointing results. A promising evidence-based and

The Effect of Probiotics on the Immune Status, Diarrhea and Bacterial Vaginosis Cure Rate Among HIV Patients

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Ingia / Ingia

Background: Two third of all people infected with HIV live in Sub-Saharan Africa. A region also affected with a great burden of other infectious diseases. Relatively few patients have access to anti-retroviral treatment and many suffer from debilitating diarrhea that causes their immune system to

Effectiveness of Orthokeratology in Myopia Control

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Ingia / Ingia

Orthokeratology (ortho-k), when used for partial or full correction of myopia, has been shown to slow myopic progression in children by 36-56% as compared to their spectacle or contact-lens wearing peers.1 This effect is achieved by limiting the axial elongation of the eye,1, 2,3, 4 which is of

High-dose Vitamin D Supplements in Older Adults

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Ingia / Ingia

1. General Design This Phase 2 randomized clinical trial of high-dose vs. standard dose Vitamin D (VitD) supplementation aims to prove feasibility of the intervention in a diverse community-recruited cohort and to provide an estimate of the effect sizes of treatment on cognitive change and brain MRI

Efficacy and Safety of Shea Nut Oil in Hemophilic Arthropathy

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Ingia / Ingia

Hemophilia is an X-linked recessive bleeding disorder caused by a deficiency of coagulation factor VIII (hemophilia A) or IX (hemophilia B). Severe hemophilia patients may have frequent spontaneous bleeding episodes such as joint and muscle bleeding. Repeated joint bleeding leads to chronic

Ketorolac Versus Ibuprofen to Treat Painful Episodes of Sickle Cell Disease

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Ingia / Ingia

BACKGROUND: SCD is a common disorder among African Americans and other minority groups. It is characterized by chronic anemia and episodic vaso-occlusive crises. The most common of these crises is the painful crisis. Current treatment of the painful crisis includes rest, hydration, and analgesic

The ARIC MRI Study

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Ingia / Ingia

BACKGROUND: Although the clinical manifestations of cerebrovascular disease (CVD) typically appear acutely, the deleterious effects of CVD on brain structure and function likely begin in a presymptomatic fashion at a younger age than clinical strokes. In an effort to characterize the prevalence,

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