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Cross-over Study to Evaluate the Palatability of New Orally Disintegrating Tablets (ODTs) of Praziquantel (PZQ) and L-PZQ Versus Current PZQ Tablets in African Children Age 6-11 Years

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Ingia / Ingia

Initially pupils will be invited with their parents to school where they will be asked to give consent/assent in to the study and they will be instructed on how to follow up the taste study procedures. Enrollments will occur in the health facilities in Ikwiriri/Kibiti at the end of successive

Evaluation of a Brief Tailored Motivational Intervention to Prevent Early Childhood Caries

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Ingia / Ingia

The principal theme of the DDHP is to investigate why some African-American children and their main caregivers have better oral health than others who live in the same community. This question dictates the design of individual projects to understand the determinants of oral health disparities. The

Caries Prophylaxis With Flairesse Fluoride Varnish

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Ingia / Ingia

Dental caries is a chronic disease that affects most adults and children worldwide. It is especially problematic for people with a low economic status, limited access to oral health care services and a lack of awareness for the need for preventive measures. To improve oral health, it has been

Glass Ionomer Sealant and Fluoride Varnish Study to Prevent Early Childhood Caries

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Ingia / Ingia

Community-based, stratified (by location) randomized clinical trial (RCT) to determine the relative efficacy of topically applied fluoride varnish (FV) applications alone vs FV with fluoride-releasing glass ionomer (GI) sealants on occlusal surfaces of primary molars in reducing the caries incidence

Relationship of Periodontal Disease Treatment and Type 2 Diabetes Mellitus in the Gullah Population

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Ingia / Ingia

Specific Aim 1: To ascertain the rate of periodontal disease progression on poorly controlled Type 2 diabetic Gullah African American patients as compared to well-controlled Gullah African American patients. The host inflammatory response appears to be the critical determinant for susceptibility and

Interpregnancy Care Project-Mississippi (IPC-M)

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Ingia / Ingia

In the United States, Low Birth Weight (LBW; less than 2500 grams) delivery is the leading cause of infant mortality for African Americans. In addition, Very Low Birth Weight (VLBW; less than 1500 grams) deliveries frequently result in severe chronic health problems and lifelong disability in the

Oral Health Education Program

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Ingia / Ingia

The Detroit Dental Health Project (DDHP) is a seven-year research study designed to identify the determinants of variation in prevalence and incidence of dental caries among low-income African-American children in Detroit. The children were randomly selected from housing units located in the lowest

Effectiveness of Modified Class IV Atraumatic Restorative Treatment

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Ingia / Ingia

Atraumatic Restorative Treatment (ART) has become an evidence-based treatment in class I caries cavities for countries with developing dental infrastructure. Though epidemiological data also demonstrate restorative treatment needs in anterior teeth in several African countries, scientific evidence

Coordinated Oral Health Promotion (CO-OP) Chicago

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Ingia / Ingia

Dental caries is the most common chronic disease of childhood; an estimated 28% of children nationally aged 5 years and below have untreated dental disease. Pediatric dental caries are associated with pain, more severe infections, malnutrition, speech difficulties, poor school performance, cosmetic

Allograft Fibrosis Following Pediatric Cardiac Transplantation

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Ingia / Ingia

There has been recent evidence that demonstrates a significant racial disparity in outcomes following pediatric heart transplantation.Differences in fibrosis or its regulation may offer an explanation to these differences.Just as the pathologic alterations of cardiac connective tissue in the

Preventing Health Disparities During Pregnancy Through Vitamin D Supplementation

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Ingia / Ingia

This project, comprised of discrete studies, expert evaluation and translation for public health campaign, promotes racial health equity for pregnant women. A strong racial disparity in the US surrounds vitamin D status: African American women have 20-fold and Hispanic women 2.4-fold greater risk of

Effects of Sucralose on Drug Absorption and Metabolism (The SweetMeds Study)

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Ingia / Ingia

Background: Consumption of non-nutritive sweeteners (NNS) has dramatically increased worldwide and is more prevalent in women than men. Similarly, obesity rates have continued to rise, most notably in minorities. Since NNS consumption has been linked to obesity, we propose studying NNS effects

Cigarette Smoking and Oral Microbiota

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Ingia / Ingia

The oral microbial community (the microbiota), is centrally related to nutrition, metabolism, immunity, inflammation, and endocrine balance. Cigarette smoking is associated with serious health outcomes including cancer, cardiovascular disease and chronic lung disease. However, little is known about

Training-induced Increased Left Ventricular Trabeculation

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Ingia / Ingia

Background of Left Ventricular Non-Compaction Cardiomyopathy Left Ventricular Non-Compaction Cardiomyopathy (LVNC) is a myocardial disorder defined by increased left ventricular (LV) trabeculation and intertrabecular recesses communicating with the LV cavity. The condition is associated with

Alginate Dressings Versus Gauge Dressings After Pilonidal Cyst Resection: Examination of the Quality of Life

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Ingia / Ingia

Pilonidal cyst was first described by Hodges in 1880. The disease of pilonidal cyst is also known as "Jeep disease", due to the fact that, during World War II (1941-1945), several American soldiers (about 80,000) suffered from this disease, because, either they were driving for long hours on uneven,

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