african/phosphatase

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African-American Bone Metabolism and Lactation Study

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Ingia / Ingia

Pregnancy and lactation are both states of altered maternal calcium and bone metabolism which may have a significant impact on the development of peak bone mass. While these two states are characterized by different hormonal environments, both have been associated with significant bone loss. The

Longitudinal Lactation Bone Density Study

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Ingia / Ingia

Pregnancy and lactation are both states of altered maternal calcium metabolism. Maternal calcium mobilization is essential in the provision of an adequate calcium supply to the developing fetus and infant. During pregnancy approximately 30 grams of calcium is required for fetal skeletal development.

3-Week Parathyroid Hormone-related Protein (PTHrP) Dose Escalation Study in Post-Menopausal Women

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Ingia / Ingia

Parathyroid Hormone-related Protein (1-36) or PTHrP is a neuroendocrine peptide which shares significant homology with the only currently FDA approved anabolic agent for the treatment of osteoporosis: parathyroid hormone(1-34) or PTH. PTH, when given alone, has shown to increase lumbar spine bone

Phase 1 Studies of AQ-13, a Candidate Aminoquinoline Antimalarial, in Comparison With Chloroquine

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Ingia / Ingia

Study Population: Healthy young men and women 21-45 years of age who are taking no chronic medications with the exception of birth control pills will be invited to participate in this Phase 1 Study at the Tulane/LSU/Charity Hospital General Clinical Research Center (GCRC) in New Orleans. Exclusion

Morbidity, Mortality, Short and Long-term Survival of Hemodialysis End-stage Kidney Disease Patients in Central Tanzania

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Ingia / Ingia

Background End-stage renal disease: End-stage renal disease is the eighteenth cause of deaths worldwide. Despite fairly stable incidences, the prevalence of End-stage renal disease on renal replacement therapy has doubled from 1990 to 2010 and the toll is expected to rise further in the coming

A Clinical Trial to Evaluate the Efficacy and Safety of Two Aramchol Doses Versus Placebo in Patients With NASH

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Ingia / Ingia

This is a multicenter, Phase IIb, randomized, double blind, placebo-controlled study designed to evaluate the efficacy and safety of two Aramchol doses in subjects that are 18 to 75 years of age, with Non-Alcoholic Steatohepatitis (NASH) confirmed by liver biopsy performed in a period of 6 months

High-dose Intravenous Vitamin C as an Adjunctive Treatment for Sepsis in Rwanda

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Ingia / Ingia

General objectives: This study will primarily determine if it is possible to perform a powered randomized control trial of the administration of intravenous high-dose vitamin C for the treatment of sepsis or septic shock in the tertiary care setting in Rwanda. Additionally, the study will also

The University of Zimbabwe College of Health Science (UZ-CHS) BIRTH COHORT Study

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Ingia / Ingia

Over one million infants are born to HIV-1-infected women every year in Sub Saharan Africa. In Zimbabwe, annual births stand at 379,000 with approximately 48,000 infants being born every year to HIV-1-infected women on lifelong highly active antiretroviral therapy (HAART). Concerns have been

The Effect of Vitamin D and Calcium on Bone in Pediatric HIV

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Ingia / Ingia

A.1.a. Introduction This is a prospective, randomized, double-blind clinical trial designed to evaluate the effect of 24 months of supplementation with vitamin D3 and calcium on bone mass accrual in HIV-infected children and adolescents. A.1.b. Subject recruitment i. HIV-infected subjects on will be

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Herbal & Natural Medicine

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