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A natural product atalantraflavone inhibits non-small cell lung cancer progression via destabilizing Twist1.

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Ingia / Ingia

The non-small cell lung cancer (NSCLC) represents a malignant type of cancer worldwide. The atalantraflavone (AFL) is a natural product isolated from leaves of Atalantia monophylla (L.) DC. However, the function of atalantraflavone in NSCLC is still elusive. In present work, we have unraveled a

Styrenes from the Seeds of Atalantia monophylla.

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Ingia / Ingia

Four new dimeric styrenes, 1-4, were isolated from an EtOAc crude extract of the seeds of Atalantia monophylla. The biosynthetic pathway of 1 is proposed to involve a [2 + 2] cycloaddition, while 2-4 may be generated via a polar mechanism with a carbocation

New limonophyllines A-C from the stem of Atalantia monophylla and cytotoxicity against cholangiocarcinoma and HepG2 cell lines.

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Ingia / Ingia

Three new limonoids, limonophyllines A-C (1, 4 and 5), along with two known limonoids (2 and 3) and 11 acridone alkaloids (6-16) were isolated from the stems of Atalantia monophylla. All isolates were evaluated against cholangiocarcinoma, KKU-M156, and HepG2 cancer cell lines. Compounds 12, 14 and

Antigenotoxic and apoptotic activities of essential oil of Atalantia monophylla Correa.

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Ingia / Ingia

OBJECTIVE To study antigenotoxic and apoptotic activities of hydrodistilled essential oil from the leaves of Atalantia monophylla Correa. METHODS Antigenotoxic activity of essential oil was tested against hydrogen peroxide (100 μM)-induced deoxyribonucleic acid (DNA) damage in 3T3-L1 cells. Cervical

Constituents of the root bark of Severinia buxifolia collected in Hainan.

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Ingia / Ingia

Two new tetranortriterpenoids, 7-isovaleroylcycloseverinolide (1) and 7-isovaleroylcycloepiatalantin (2), together with 28 known compounds, were isolated and characterized from the root bark of Severinia buxifolia collected in Hainan. The structures of 1 and 2 were elucidated on the basis of

Bioactive Phenolic Components from the Twigs of Atalantia buxifolia.

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Ingia / Ingia

Five new compounds named buxifoximes A-C (1-3), buxifobenzoate (4), and 7- O-(7'-peroxygeranyl) coumarin (5), together with 25 known compounds, were identified from the twigs of Atalantia buxifolia. Compounds 1-3 are unique secondary metabolites with the aldoxime functionality. The structures of the

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Herbal & Natural Medicine

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