benzoxazole/saratani

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6-O-substituted benzoxazole and benzothiazole compounds and methods of inhibiting CSF-1R signaling

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala

Ingia / Ingia

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to 6-O-substituted benzoxazole and benzothiazole compounds, their tautomers, stereoisomers, solvates, oxides, esters, metabolites, and prodrugs, and to the pharmaceutically acceptable salts thereof. This invention

Benzoxazoles and oxazolopyridines being useful as janus kinases inhibitors

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Ingia / Ingia

This application is a U.S. National Phase filing of International Serial No. PCT/EP2007/007983 filed Sep. 13, 2007, and claims priority to EP Application Serial No. 06120733.8 filed Sep. 15, 2006, the content of which are incorporated herein by reference in their entirety. The invention relates to

Benzoxazole kinase inhibitors and methods of use

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala

Ingia / Ingia

BACKGROUND OF THE INVENTION The activity of cells can be regulated by external signals that stimulate or inhibit intracellular events. The process by which stimulatory or inhibitory signals are transmitted into and within a cell to elicit an intracellular response is referred to as signal

Benzoxazole kinase inhibitors and methods of use

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Ingia / Ingia

Therapeutic benzoxazole compounds

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Ingia / Ingia

TECHNICAL FIELD The present invention is directed to a series of ligands, and more particularly to estrogen receptor-.beta. ligands which have better selectivity than estrogen for the estrogen receptor-.beta. over the estrogen receptor-.alpha., as well as to methods for their production and use in

Benzothiazole or benzoxazole compounds as sumo activators

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Ingia / Ingia

TECHNICAL FIELD The present application relates to SUMO activators, which can enhance SUMOylation of SERCA2a, which are useful in the treatment of heart failure, cardiovascular diseases, cancer, neurodegenerative disorders, viral infection, bacterial infection, liver disease, inflammation, and other

Benzothiazole or benzoxazole compounds as SUMO activators

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala

Ingia / Ingia

Benzothiazole-and benzoxazole-4, 7-dione derivatives and their use as dcd25 phosphatase inhibitors

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala

Ingia / Ingia

This application is a 371 of PCT/FR02/04544 filed Dec. 24, 2002. A subject of the present invention is novel derivatives of benzothiazole-4,7-dione and benzooxazole-4,7-dione, which inhibit the cdc25 phosphatases, in particular cdc25-C phosphatase, and/or CD45 phosphatase. Control of the transition

CSF-1R inhibitors, compositions, and methods of use

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala

Ingia / Ingia

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to 6-O-substituted benzoxazole and benzothiazole CSF-1R inhibitory compounds, their oxides, esters, prodrugs, solvates, or pharmaceutically acceptable salts thereof. This invention also relates to compositions of the

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