berbamine/infarction

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Berbamine ameliorates isoproterenol-induced myocardial infarction by inhibiting mitochondrial dysfunction and apoptosis in rats.

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Ingia / Ingia

Berbamine (BBM), a bisbenzylisoquinoline alkaloid from roots, bark, and stem of Berberis plant such as Berberis aristata has a wide range of pharmacological activities. However, the evidence for the cardioprotective effect of BBM is inadequate and the molecular mechanism of BBM remains unclear. This

[Protective effect of berbamine on myocardial infarction in rabbits and rats].

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Ingia / Ingia

[Electrophysiological effects of berbamine on ischemic ventricular tachyarrhythmia].

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Ingia / Ingia

The effects of berbamine (Ber, 10 mg.kg-1 iv) on ischemic ventricular tachyarrhythmia and electrophysiologic consequences in both normal and ischemic myocardia were studied in the open-chest dogs subjected to programmed electrical stimulation (PES) on 5-8 d after acute myocardial infarction. Its

Berbamine postconditioning protects the heart from ischemia/reperfusion injury through modulation of autophagy.

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Ingia / Ingia

Pretreatment of berbamine protects the heart from ischemia/reperfusion (I/R) injury. However it is unknown whether it has cardioprotection when given at the onset of reperfusion (postconditioning (PoC)), a protocol with more clinical impact. Autophagy is upregulated in I/R myocardium and exacerbates

Berbamine protects the heart from ischemia/reperfusion injury by maintaining cytosolic Ca(2+) homeostasis and preventing calpain activation.

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Ingia / Ingia

BACKGROUND Berbamine, a natural compound from Barberry, was reported to protect myocardium from ischemia/reperfusion (I/R) injury, but the underlying mechanisms are largely unknown. RESULTS Berbamine pretreatment from 10 to 100nmol/L concentration-dependently improved post-ischemic myocardial

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