cerbera thevetia/glycoside

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New cytotoxic cardenolide glycoside from the seeds of Cerbera manghas.

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Ingia / Ingia

A new cytotoxic cardenolide glycoside, 3beta-O-(2'-O-acetyl-alpha-L-thevetosyl)-14beta-hydroxy-7-en-5beta-card-20(22)-enolide, (7,8-dehydrocerberin), together with five known cardenolides, 17beta-neriifolin, deacetyltanghinin, tanghinin, cerberin and 2'-O-acetyl-cerleaside A were isolated from the

Naturally occurring cardiac glycosides.

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Ingia / Ingia

Cardiac glycoside poisoning from the ingestion of plants, particularly of oleanders, occurs with reasonable frequency in tropical and subtropical areas. We have assessed a variety of plant specimens for their cardiac glycoside content by means of radioimmunoassays with antibodies that differ in

Cytotoxic cardenolide glycoside from the seeds of Cerbera odollam.

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Ingia / Ingia

A cardenolide glycoside, 3 beta-O-(2'-O-acetyl-l- thevetosyl)-15(14-->8)-abeo-5 beta-(8R)-14-oxo-card-20(22)-enolide (2'-O-acetyl cerleaside A), was isolated from a methylene chloride extract of the seeds of Cerbera odollam, together with four known compounds: cerleaside A, 17 alpha-neriifolin, 17

[The separation and identification of cardiac glycosides in the kernal of Cerbera odollam (author's transl)].

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Ingia / Ingia

Cardiac glycoside poisoning following suicidal ingestion of Cerbera manghas.

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Ingia / Ingia

[Studies on the constituents of Apocynaceae plants; Isolation of flavonol glycosides and some other components from the leaves of Cerbera manghas L; (1) (author's transl)].

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Ingia / Ingia

Neriifolin from seeds of Cerbera manghas L. induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells.

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Ingia / Ingia

The effects of neriifolin, a cardiac glycoside from Cerbera manghas L. on various end-points of oncologic relevance (cell growth, cell cycle regulation, and apoptosis in HepG2 cells) were investigated. Neriifolin reduced viability of HepG2 cells, induced S and G2/M phase arrests of the cell cycle,

β-D-Glucosyl-(1-4)-α-L-thevetosides of 17β-digitoxigenin from seeds of Cerbera manghas L. induces apoptosis in human hepatocellular carcinoma HepG2 cells.

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Ingia / Ingia

β-D-Glucosyl-(1-4)-α-L-thevetosides of 17β-digitoxigenin (GHSC-73) is a cardiac glycoside isolated from the seeds of Cerbera manghas L. GHSC-73 reduced viability of HepG2 cells in a time- and dose-dependent manner without decreasing the viability of Chang human liver cells and Swiss albino 3T3

Acaricidal activity against Panonychus citri and active ingredient of the mangrove plant Cerbera manghas.

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Ingia / Ingia

Cerbera manghas is a mangrove plant which possesses comprehensive biological activities. A great deal of research has been undertaken on the chemical constituents and medical functions of C. manghas; insecticidal and antifungal activities have also been reported, but the acaricidal activity has not

2'-epi-2'-O-Acetylthevetin B extracted from seeds of Cerbera manghas L. induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells.

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Ingia / Ingia

2'-epi-2'-O-Acetylthevetin B (GHSC-74) is a cardiac glycoside isolated from the seeds of Cerbera manghas L. We have demonstrated that GHSC-74 reduced the viability of HepG2 cells in a time- and dose-dependent manner. The present study was designed to explore cellular mechanisms whereby GHSC-74 led

Tanghinigenin from seeds of Cerbera manghas L. induces apoptosis in human promyelocytic leukemia HL-60 cells.

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Ingia / Ingia

Tanghinigenin, a cardiac glycoside, is isolated from the seeds of Cerbera manghas L. In this study, we demonstrated that tanghinigenin reduced the viability of human promyelocytic leukemia HL-60 cells in a time- and dose-dependent manner, and efficiently induced apoptosis in HL-60 cells as evidenced

Fatality Following Intentional Ingestion of Cerbera odollam Seeds.

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Ingia / Ingia

Seeds from the mangrove plant Cerbera (C.) odollam, known as the "suicide tree," are responsible for a significant number of plant deaths worldwide but are not well recognized in Western medicine. Cerberin is a cardiac glycoside concentrated in the plant's seeds, which causes disrupted cardiac

The In Vitro Anti-Cancer Activities of 17βH-Neriifolin Isolated from Cerbera odollam and Its Binding Activity on Na+,K+-ATPase.

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Ingia / Ingia

17βH-neriifolin, a cardiac glycoside compound had been successfully isolated from Cerbera odollam leaves based on bioassay guided isolation procedure. The compound was tested against breast (MCF-7, T47D), colorectal (HT-29), ovarian (A2780, SKOV-3) and skin (A375) cancer cell lines that gave IC50

Cardiac Toxicity from Intentional Ingestion of Pong-Pong Seeds (Cerbera Odollam).

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Ingia / Ingia

A variety of plants contain cardiac glycosides. This has resulted in many of them being used to commit suicide. In southeast Asia, Cerebera odollam (pong-pong or suicide tree) is frequently used for suicidal ingestion. Seeds, or kernels, of this plant can cause hyperkalemia, heart block, and death

Cerbera odollam toxicity: A review.

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Ingia / Ingia

Cerbera odollam is a plant species of the Apocynaceae family. It is often dubbed the 'suicide tree' due to its strong cardiotoxic effects, which make it a suitable means to attempt suicide. The plant grows in wet areas in South India, Madagascar, and Southeast Asia; and its common names include

Iliyotangulia
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