chrysosplenol c/miliusa

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NakalaMajaribio ya klinikiHati miliki

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Chrysosplenol C increases contraction in rat ventricular myocytes.

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Ingia / Ingia

Chrysosplenol C (4',5,6-trihydroxy-3,3',7-trimethoxyflavone) is a flavone contained in several medicinal plants including Miliusa balansae and Pterocaulon sphacelatum. This compound is known to have an antiviral effect and show cytotoxic activity in several cell lines. In the present study, we

Exploration of Pharmacophore in Chrysosplenol C as Activator in Ventricular Myocyte Contraction.

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Ingia / Ingia

Chrysosplenol C (4',5,6-trihydroxy-3,3',7-trimethoxyflavone) isolated from Miliusa balansae has unique structural features as a reversible inotropic agent independent of β-adrenergic signaling and with selective activation of cardiac myosin ATPase. Hence, a series of chrysosplenol analogues were

A new flavone and cytotoxic activity of flavonoid constituents isolated from Miliusa balansae (Annonaceae).

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Ingia / Ingia

A new flavone named miliufavol [8-(2-hydroxybenzyl)-5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,7-dimethoxy-4H-chromen-4-one or 8-C-(o)-hydroxybenzylpachypodol] from Miliusa balansae (Annonaceae) was isolated and structurally elucidated by spectroscopic means besides four known flavones: ombuine,

Homogentisic acid derivatives from Miliusa balansae.

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Ingia / Ingia

The new homogentisic acid derivatives miliusol (1b) and miliusolide (2) from Miliusa balansae were isolated and structurally determined by spectroscopic means. The relative configurations of the new 1b and its known acetate 1a were established. Furthermore, the symmetric ether

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