clausenamide/neurodegenerative diseases

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Recent advances in the study of (-)clausenamide: chemistry, biological activities and mechanism of action.

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Ingia / Ingia

Clausenamide (clau) is one of seven novel compounds isolated from Clausena lansium (Lour) skeels. Clau is unusual in that it contains 4 chiral centers yielding 8 pairs of enantiomers. After identification of the configuration of these enantiomers, the synthesis of 16 enantiomers, including optically

The anti-dementia drug candidate, (-)-clausenamide, improves memory impairment through its multi-target effect.

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Ingia / Ingia

Multi-target drugs, such as the cocktail therapy used for treating AIDS, often show stronger efficacy than single-target drugs in treating complicated diseases. This review will focus on clausenamide (clau), a small molecule compound originally isolated from the traditional Chinese herbal medicine,

[Culture of neural stem cells from cerebral cortex of rat embryo and effects of drugs on the proliferation ability of stem cells].

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Ingia / Ingia

OBJECTIVE To establish culture procedures of neural stem cells from embryonic rat brain, determine their stem-cell characteristics and observe the effects of several compounds on their proliferation ability. METHODS Firstly, a stem cell culture system was set up from embryonic rat cortex. The cells

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Herbal & Natural Medicine

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