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common/tyrosine

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10 matokeo

Styryl-substituted pyridyl compounds which inhibit EGF receptor tyrosine kinase

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
FIELD OF THE INVENTION This invention relates to the inhibition of cell proliferation. More specifically, this invention relates to the use of styryl-substituted monocyclic and bicyclic heteroaryl compounds in inhibiting cell proliferation, including compounds which are useful protein tyrosine

Styryl-substituted monocyclic and bicyclic heteroaryl compounds which inhibit EGF receptor tyrosine kinase

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
FIELD OF THE INVENTION This invention relates to the inhibition of cell proliferation. More specifically, this invention relates to the use of styryl-substituted monocyclic and bicyclic heteroaryl compounds in inhibiting cell proliferation, including compounds which are useful protein tyrosine

Styryl-substituted monocyclic and bicyclic heteroaryl compounds which inhibit EGF receptor tyrosine kinase

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
FIELD OF THE INVENTION This invention relates to the inhibition of cell proliferation. More specifically, this invention relates to the use of styryl-substituted monocyclic and bicyclic heteroaryl compounds in inhibiting cell proliferation, including compounds which are useful protein tyrosine

Identification and characterization of reflectin proteins from squid reflective tissues

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
FIELD OF THE INVENTION The invention relates generally to a new family of proteins that compose a subcellular structure that confers reflectivity to squid tissues. More specifically, the invention relates to squid reflectin proteins and active portions and repeat units thereof. BACKGROUND OF THE

Bovine ABCG2 gene missense mutations and uses thereof

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
BACKGROUND Although many studies have demonstrated linkage between genetic markers and quantitative trait loci (QTL) in commercial animal populations, the actual DNA polymorphisms responsible for the observed effects--a quantitative trait nucleotide (QTN), has been identified in only a single case

Materials and methods for suppressing and/or treating neurofibroma and related tumors

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
FIELD OF THE INVENTION Various aspects and embodiments disclosed herein relate generally to the modeling, treatment, prevention and diagnosis of diseases characterized by the formation of tumors, for example, neurofibroma. BACKGROUND Mutations in the NF1 tumor suppressor gene cause neurofibromatosis

Materials and methods for suppressing and/or treating neurofibroma and related tumors

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
FIELD OF THE INVENTION Various aspects and embodiments disclosed herein relate generally to the modeling, treatment, prevention and diagnosis of diseases characterized by the formation of tumors, for example, neurofibroma. BACKGROUND Mutations in the NF1 tumor suppressor gene cause neurofibromatosis

Mutations in DSTYK cause dominant urinary tract malformations

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
BACKGROUND Congenital abnormalities of the kidney and the urinary tract (CAKUT) are the most common cause of pediatric kidney failure. These disorders are highly heterogenous, and their etiology is poorly understood. Many forms of CAKUT are familial, but because they may be asymptomatic, they

Human monocyte chemoattractant protein-1 (MCP-1) derivatives

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
BACKGROUND Chemokines are proinflammatory cytokines that are chemoattractants and activators of specific types of leukocytes. Members of this family share common structural motifs, in particular the positions of four cysteines, as well as other highly conserved regions of primary structure. Despite

Association between the acid phosphatase (ACP1) gene and Alzheimer's disease

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
FIELD OF THE INVENTION This invention relates generally to the field of human genetics. More specifically, the invention relates to human germline mutations or polymorphisms in the ACP1 gene, methods and materials used to isolate and detect said mutations or polymorphisms and further to their use in
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