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Bioassay-guided fractionation of the cytotoxic ethyl acetate fraction of the sequential methanol extract from the leaves and twigs of Dasymaschalon sootepense led to the isolation of a new 7-hydroxy aporphine alkaloid, 6a,7-dehydrodasymachaline (1) along with the five known compounds
A novel aristololactam alkaloid, dasymalactam A (1), together with nine known analogues (2-10), were isolated from the roots of Dasymaschalon rostratum. Their structures were elucidated by IR, NMR and MS spectrums and comparisons with data reported in the literature. All
Bioassay-guided fractionation of the cytotoxic ethyl acetate extract from the stems of Dasymaschalon blumei (Annonaceae) led to the isolation of four aristololactam alkaloids, including the hitherto unknown 3,5-dihydroxy-2,4-dimethoxyaristolactam (1), as well as the three known compounds,
OBJECTIVE
To study the chemical components and antitumor activities of essential oil from the fruits of Dasymaschalon trichophorum.
METHODS
The essential oil from the fruits of Dasymaschalon trichophorum was extracted by steam-stilling and analyzed by GC-MS. The inhibitory effect of extract of