Use of the antimicrobial cathelicidin peptide II-37, N-terminal fragments of LL-37 or extended sequences of LL-37 having 1-3 amino acids in the C-terminal end, for stimulating proliferation of epithelial and stromal cells and thereby healing of wounds, such as chronic ulcers. The cytotoxic effect of LL-37 may be reduced by including a bilayer-forming polar lipid, especially a digalactosyldiacylglycerol, in pharmaceutical compositions and growth media comprising LL-37.

Lipopeptide AB

Use of the cathelicidin LL-37 and derivatives thereof for wound healing

Stahle-Backdahl; Mona

Heilborn; Johan

Carlsson; Anders

Bogentoft; Conny

Use of the antimicrobial cathelicidin peptide ll-37, N-terminal fragments of LL-37 or extended sequences of LL-37 having 1-3 amino acids in the C-terminal end, for stimulating proliferation of epithalial and stromal cells and thereby healing of wounds, such as chronic ulcers. The cytotoxic effect of LL-37 may be reduced by including a bilayer-forming polar lipid, especially a digalactosyldiacylglycerol, in pharmaceutical compositions and growth media comprising LL-37.

digalactosyldiacylglycerol/ulcer

Use of the cathelicidin LL-37 and derivatives thereof for wound healing

Use of the cathelicidin LL-37 and derivatives thereof for wound healing

Use of the cathelicidin LL-37 and derivatives thereof for wound healing

Use of the cathelicidin LL-37 and derivatives thereof for wound healing

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