endolymphatic hydrops/arginine

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Effect of electroacupuncture on arginine vasopressin-induced endolymphatic hydrops.

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Ingia / Ingia

ractText>To investigate the influence of electroacupuncture (EA) on experimentally induced endolymphatic hydrops (EH) in guinea pigs, and elucidate the association between the dehydrating effect of EA and changes in stria vascularis ultrastructure and expression of vasopressin type 2 receptor

Arginine vasopressin-aquaporin-2 pathway-mediated dehydration effects of electroacupuncture in guinea pig model of AVP-induced endolymphatic hydrops.

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Ingia / Ingia

OBJECTIVE To investigate the effects of electroacupuncture (EA) on endolymphatic hydrops (EH) and the regulation of arginine vasopressin (AVP)-aquaporin-2 (AQP2) pathway in guinea pigs. METHODS EH was induced in male guinea pigs by an intraperitoneal injection of AVP. For the treatment, EA was

[Arginine vasopressin-aquaporin2 signal pathway and endolymphatic hydrops].

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Ingia / Ingia

Effects of arginine vasopressin on auditory brainstem response and cochlear morphology in rats.

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Ingia / Ingia

OBJECTIVE This study was conducted to evaluate the relationship between hearing and cochlear histopathology after arginine vasopressin administration in rats. METHODS A total of 30 Wistar rats were injected with either 0.02 unit/g of arginine vasopressin or the same amount of isotonic saline

Summating potential in the guinea pig cochlea after perilymphatic perfusion with arginine-vasopressin.

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Ingia / Ingia

We hypothesized that arginine-vasopressin (AVP), the natural vasopressin in the guinea pig, might increase the cochlear summating potential, indicating an increase in endolymphatic volume. Guinea pig cochleas were perfused with artificial perilymph for 15 min, with or without AVP (2 x 10(-6) M). In

[Effect of vasopressin on aquaporin 7 expression in rat inner ear].

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Ingia / Ingia

OBJECTIVE To study the effect of vasopressin on aquaporin 7 (AQP7) expression in rat inner ear and reveal the possible role of aquaporins in the formation of endolymphatic hydrops induced by vasopressin. METHODS Wistar rats were intraperitoneally injected with 50 microg/kg arginine vasopressin once

Vasopressin and oxytocin receptor mRNAs are expressed in the rat inner ear.

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Ingia / Ingia

The cause of endolymphatic hydrops, a characteristic finding in Menière's disease, is not known. To study the possible involvement of the neurohormones vasopressin and oxytocin in this condition, we investigated whether transcripts of the genes encoding the arginine vasopressin (AVP) and oxytocin

Effects of vasopressin on gene expression in rat inner ear.

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Ingia / Ingia

Vasopressin regulates water excretion from the kidney by increasing water permeability of the collecting duct as a hormone secreted from the posterior pituitary. A clinical study reported that plasma levels of arginine vasopressin were significantly higher in patients suffering from Meniere's

Claudin expression in the rat endolymphatic duct and sac - first insights into regulation of the paracellular barrier by vasopressin.

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Ingia / Ingia

Hearing and balance functions of the inner ear rely on the homeostasis of the endolymphatic fluid. When disturbed, pathologic endolymphatic hydrops evolves as observed in Menière's disease. The molecular basis of inner ear fluid regulation across the endolymphatic epithelium is largely unknown. In

Ménière's Disease Pathophysiology: Endolymphatic Sac Immunohistochemical Study of Aquaporin-2, V2R Vasopressin Receptor, NKCC2, and TRPV4.

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Ingia / Ingia

Objectives Endolymphatic sac (ELS) pathophysiology in Ménière's disease (MD) remains poorly understood. We identified from the literature a group of proteins expressed on the ELS and involved in endolymph volume regulation: aquaporin-2 (AQP2), vasopressin receptor V2R, sodium potassium chloride

Autoregulation of cochlear blood flow in the hydropic guinea pig.

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Ingia / Ingia

Previous data suggest that regulation of cochlear blood flow (CBF) may be abnormal in the hydropic guinea pig. The purpose of this study was to employ the technique of anterior inferior cerebellar artery (AICA) occlusion to measure CBF autoregulation in experimental endolymphatic hydrops. This study

Aquaporins as potential drug targets for Meniere's disease and its related diseases.

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Ingia / Ingia

The homeostasis of water in the inner ear is essential for maintaining function of hearing and equilibrium. Since the discovery of aquaporin water channels, it has become clear that these channels play a crucial role in inner ear fluid homeostasis. Indeed, proteins or mRNAs of AQP1, AQP2, AQP3,

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