farber lipogranulomatosis/disulfide

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NakalaMajaribio ya klinikiHati miliki

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2 matokeo

Zebrafish acid ceramidase: Expression in Pichia pastoris GS115and biochemical characterization.

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Ingia / Ingia

Acid ceramidase (N-acylsphingosine deacylase EC 3.5.1.23; AC) catalyzes the hydrolysis of ceramide into sphingosine (SPH) and free fatty acid. Zebrafish acid ceramidase (AC) has 60% homology with the human AC). Mutations in the human AC gene asah1 are known to cause Farber disease and spinal

Overexpression and mass spectrometry analysis of mature human acid ceramidase.

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Ingia / Ingia

Human acid ceramidase catalyzes the last step of lysosomal sphingolipid degradation, the hydrolysis of ceramide to sphingosine and free fatty acid. Inherited deficiency of acid ceramidase activity leads to Farber disease (Farber lipogranulomatosis). In this study, we describe the overexpression and

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Herbal & Natural Medicine

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