Fluorene / saratani

Heterocyclic-hydroxyimino-fluorene nuclei compounds and pharmaceutical compositions for inhibiting protein kinases, and methods for their use

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala

Ingia / Ingia

FIELD OF THE INVENTION This invention is directed to compounds with heterocyclic-hydroxyimino-fluorene nuclei that mediate and/or inhibit the activity of certain protein kinases, and to pharmaceutical compositions containing such compounds. The invention is also directed to the therapeutic or

9H-pyrimido[4,5-B]indoles, 9H-pyrido[4',3':4,5]pyrrolo[2,3-D]pyridines, and 9H 1,3,6,9 tetraaza-fluorenes as CHK1 kinase function inhibitors

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala

Ingia / Ingia

TECHNICAL FIELD The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain tricyclic compounds (referred to herein as TC compounds), and especially certain 9H-pyrimido[4,5-b]indole, 9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyridine, and

Derivatives of fluorene, anthracene, xanthene, dibenzosuberone and acridine and uses thereof

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala

Ingia / Ingia

FIELD OF THE INVENTION The present invention relates to the field of novel compounds useful for the treatment of cancer and methods of use thereof. BACKGROUND OF THE INVENTION The Wnt/beta-catenin signaling pathway is recognized as one of the key signaling pathways in cancer and as a valid target

Derivatives of fluorene, anthracene, xanthene, dibenzosuberone and acridine and uses thereof

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala

Ingia / Ingia

FIELD OF THE INVENTION The present invention relates to the field of novel compounds useful for the treatment of cancer and methods of use thereof. BACKGROUND OF THE INVENTION The Wnt/beta-catenin signaling pathway is recognized as one of the key signaling pathways in cancer and as a valid target

Derivatives of fluorene, anthracene, xanthene, dibenzosuberone and acridine and uses thereof

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala

Ingia / Ingia

FIELD OF THE INVENTION The present invention relates to the field of novel compounds useful for the treatment of cancer and methods of use thereof. BACKGROUND OF THE INVENTION The Wnt/beta-catenin signaling pathway is recognized as one of the key signaling pathways in cancer and as a valid target

Certain aryl-ureido anti-cancer agents

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala

Ingia / Ingia

BACKGROUND OF THE INVENTION Chemotherapeutic agents currently used for antitumor therapy are selected for their toxicity towards rapidly proliferating cells. Most of them cause undesirable systemic effects such as cardiac or renal toxicity, marrow aplasia, alopecia, nausea and vomiting. During the

Certain carbanate anti-cancer agents

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala

Ingia / Ingia

BACKGROUND OF THE INVENTION Chemotherapeutic agents currently used for antitumor therapy are selected for their toxicity towards rapidly proliferating cells. Most of them cause undesirable systemic effects such as cardiac or renal toxicity, marrow aplasia, alopecia, nausea and vomiting. During the

Fluorene compound and pharmaceutical use thereof

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala

Ingia / Ingia

TECHNICAL FIELD OF THE INVENTION The present invention relates to a fluorene compound and a pharmaceutical use thereof. More particularly, the present invention relates to a compound for the prophylaxis or treatment of diabetes, cardiovascular diseases, hyperlactacidemia and cancer based on

Fluorene compound and pharmaceutical use thereof

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala

Ingia / Ingia

TECHNICAL FIELD OF THE INVENTION The present invention relates to a fluorene compound and a pharmaceutical use thereof. More particularly, the present invention relates to a compound for the prophylaxis or treatment of diabetes, cardiovascular diseases, hyperlactacidemia and cancer based on

Cyanine-sulfenates for dual phototherapy

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala

Ingia / Ingia

FIELD OF THE INVENTION The present invention relates to novel dye-sulfenate compounds, and to phototherapeutic procedures using these compounds. BACKGROUND OF THE INVENTION The use of visible and near-infrared (NIR) light in clinical practice is growing rapidly. Compounds absorbing or emitting in

Anthracene-9, 10-dione dioxime compound prodrugs and their uses

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala

Ingia / Ingia

FIELD OF THE INVENTION The present invention relates to novel prodrugs of biologically active anthracene-9, 10-dione dioxime compounds, their intermediates, methods for synthesizing, and their use to treat cancer and other diseases. BACKGROUND OF THE INVENTION Cancer is the second leading cause of

Anthracene-9, 10-dione dioxime compound prodrugs and their uses

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala

Ingia / Ingia

FIELD OF THE INVENTION The present invention relates to novel prodrugs of biologically active anthracene-9, 10-dione dioxime compounds, their intermediates, methods for synthesizing, and their use to treat cancer and other diseases. BACKGROUND OF THE INVENTION Cancer is the second leading cause of

fluorene/saratani

Heterocyclic-hydroxyimino-fluorene nuclei compounds and pharmaceutical compositions for inhibiting protein kinases, and methods for their use

9H-pyrimido[4,5-B]indoles, 9H-pyrido[4',3':4,5]pyrrolo[2,3-D]pyridines, and 9H 1,3,6,9 tetraaza-fluorenes as CHK1 kinase function inhibitors

Derivatives of fluorene, anthracene, xanthene, dibenzosuberone and acridine and uses thereof

Derivatives of fluorene, anthracene, xanthene, dibenzosuberone and acridine and uses thereof

Derivatives of fluorene, anthracene, xanthene, dibenzosuberone and acridine and uses thereof

Certain aryl-ureido anti-cancer agents

Certain carbanate anti-cancer agents

Fluorene compound and pharmaceutical use thereof

Fluorene compound and pharmaceutical use thereof

Cyanine-sulfenates for dual phototherapy

Anthracene-9, 10-dione dioxime compound prodrugs and their uses

Anthracene-9, 10-dione dioxime compound prodrugs and their uses

Hifadhidata kamili ya mimea ya dawa inayoungwa mkono na sayansi