gestational trophoblastic disease/proline

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NakalaMajaribio ya klinikiHati miliki

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2 matokeo

Infrequent mutation in tumor suppressor gene p53 in gestational trophoblastic neoplasia.

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Ingia / Ingia

In order to determine the p53 status of gestational trophoblastic neoplasia, 24 cases of molar pregnancies and two choriocarcinoma cell lines (JAR and JEG-3) were evaluated for the presence of mutations. The evaluation involved the whole coding sequence (i.e. exons 2-11) of the p53 gene with

Overexpression of iASPP is required for autophagy in response to oxidative stress in choriocarcinoma.

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Ingia / Ingia

Gestational trophoblastic disease (GTD) is a heterogeneous group of diseases developed from trophoblasts. ASPP (Ankyrin-repeat, SH3-domain and proline-rich region containing protein) family proteins, ASPP1 and ASPP2, have been reported to be dysregulated in GTD. They modulate p53

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Herbal & Natural Medicine

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