guanylate cyclase inhibitor/seizures

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NakalaMajaribio ya klinikiHati miliki

Chagua aina ya aina

3 matokeo

L-arginine potentiates excitatory amino acid-induced seizures elicited in the deep prepiriform cortex.

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala

Ingia / Ingia

Microinjection of N-methyl-D-aspartate (NMDA; 1 and 2.5 nmol) or kainate (KA; 50 pmol) into the deep prepiriform cortex elicited behavioral signs of seizure activity. No epileptiform activity was observed after deep prepiriform cortex microinjection of either L-arginine (L-Arg, 5 and 10 nmol) or its

Role of nitric oxide in anticonvulsant effects of benzodiazepines in mice.

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Ingia / Ingia

The influence of nitric oxide (NO) on anticonvulsant activity of diazepam and clonazepam was examined in the pentetrazole- and electroshock-induced seizure models in mice. Protective efficacy of the threshold dose of diazepam against pentetrazole-induced clonic and tonic seizures, and death was

In the hippocampus in vivo, nitric oxide does not appear to function as an endogenous antiepileptic agent.

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala

Ingia / Ingia

Using a reverberatory epilepiform discharge of hippocampal-parahippocampal circuits termed "maximal dentate activation", this study investigated whether the local release of nitric oxide within these circuits functions as an antiepileptic agent. Two nitric oxide synthase inhibitors (L-nitro-arginine

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Herbal & Natural Medicine

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