l ephedrine/homa

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An evaluation of l-ephedrine neurotoxicity with respect to hyperthermia and caudate/putamen microdialysate levels of ephedrine, dopamine, serotonin, and glutamate.

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Ingia / Ingia

l-Ephedrine is an active ingredient in several herbal formulations with a mechanism of action similar to amphetamine and methamphetamine. However, its potential to damage dopaminergic terminals in the caudate/putamen (CPu) has yet to be fully evaluated. The studies here used in vivo brain

L-ephedrine-induced neurodegeneration in the parietal cortex and thalamus of the rat is dependent on hyperthermia and can be altered by the process of in vivo brain microdialysis.

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Ingia / Ingia

Multiple doses of the dietary supplement L-ephedrine can cause severe hyperthermia and modest dopamine depletions in the rat brain. Since D-amphetamine treatment can result in neurodegeneration, the potential of L-ephedrine to produce similar types of degeneration was investigated. Adult male rats,

Possible involvement of beta 2-adrenoceptors in hyperthermic effect of l-ephedrine in rats.

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Ingia / Ingia

The experiments were conducted in order to examine the mechanism of hyperthermia induced by l-ephedrine in rats. beta-Adrenoceptor agonists have been known to enhance normal body temperature. Therefore, the effect of various beta-adrenoceptor agonists on body temperature in rats was examined to

Hyperthermic and anorectic effects of oxazolidines derived from L-ephedrine in rats.

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Ingia / Ingia

Oxazolidines synthesized from (-) ephedrine have been proposed as potential pro-drugs, but no pharmacological data on these compounds has been yet reported. In this study, four such compounds are tested in rats for ephedrine-like activity using the hyperthermia and anorexia models. The compounds

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Herbal & Natural Medicine

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