lantadene a/lantana camara

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Molecular structure, polymorphism, and toxicity of lantadene A, the pentacyclic triterpenoid from the hepatotoxic plant Lantana camara.

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Ingia / Ingia

Lantadene A (22 beta-angeloyloxy-3-oxo-olean-12-en-28-oic acid), a pentacyclic triterpenoid compound from lantana (Lantana camara) leaves has been obtained in two polymorphic forms I and II. Form I had white, fluffy, and rod-shaped uniform crystals. Form II particles were irregular, shining, and

Filaricidal properties of Lantana camara and Tamarindus indica extracts, and Lantadene A from L. camara against Onchocerca ochengi and Loa loa.

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Ingia / Ingia

Ivermectin is the only drug currently recommended for the treatment of onchocerciasis, the second leading infectious cause of blindness in the world. This drug kills only the first stage larvae-microfilariae (mf) of Onchocerca volvulus and is to be used cautiously in areas where Loa loa is prevalent

Lantadene A content and toxicity of the lantana plant (Lantana camara, Linn.) to guinea pigs.

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Ingia / Ingia

Lantadene A, the active principle of Lantana camara L.; isolation of lantadene B, and the oxygen functions of lantadene A and lantadene B.

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Ingia / Ingia

Nematicidal triterpenoids from Lantana camara.

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Ingia / Ingia

A new triterpene, lancamarolide (1), and seven known triterpenes, oleanonic acid (2), lantadene A (3), 11α-hydroxy-3-oxours-12-en-28-oic acid (4), betulinic acid (5), lantadene B (6), and lantaninilic acid (7) were isolated from the aerial parts of Lantana camara in the course of bioassay-guided

A review of the toxicity of Lantana camara (Linn) in animals.

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Ingia / Ingia

Lantana poisoning has been taking a heavy toll of livestock year after year. All aspects of the problem are reviewed. Lantana poisoning in cattle, sheep, buffalo, and guinea pigs caused obstructive jaundice, photosensitization, and rise in serum glutamicoxaloaetic transaminase activity. The symptoms

Triterpenes of toxic and non-toxic taxa of Lantana camara.

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Ingia / Ingia

The taxa of Lantana camara toxic to animals contain lantadene A lantadene B, whereas in two non-toxic taxa other triterpenes predominate. Several new triterpenes have been characterized. Contrary to earlier claims, lantadene A and to a lesser extent lantadene B are toxic when administered

[Studies on the chemical constituents of the leaves of Lantana camara].

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Ingia / Ingia

Six compounds were isolated from leaves of Lantana camara. On the basis of chemical and spectral (UV, IR, EI-MS, 1HNMR 13CNMR) analysis, they were identified as oleanonic acid (I), lantadene A (II), lantadene B (III), lantanilic acid (IV), icterogenin (V) and

Isolation and partial purification of Lantana (Lantana camara L.) toxins.

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Ingia / Ingia

A partially purified toxin fraction and lantadene A were obtained from Lantana camara L. leaves by batch extraction, column chromatography and fractional crystallization. Toxicity was tested in guinea pigs. The total number of chemical entities in the partially purified toxin preparation was 7, the

Effect of Lantana camara toxicity on lipid peroxidation in guinea pig tissues.

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Ingia / Ingia

Lantana intoxication of guinea pig inhibited lipid peroxidation in different tissues in the order: adrenals greater than liver greater than kidneys greater than heart greater than lungs greater than testes greater than brain. The inhibitory factor(s) appear to be present in the postmitochondrial

Levels of lantadenes, bioactive pentacyclic triterpenoids, in young and mature leaves of Lantana camara var. aculeata.

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Ingia / Ingia

Levels of the lantadene pentacyclic triterpenes were quantified in young and mature leaf samples of Lantana camara var. aculeata, by HPLC. The amount of different lantadenes (mg/100 g dry wt.) in young and mature leaf samples, respectively, was: lantadene A, 491.5 +/- 6.3, 805.9 +/- 52.8; lantadene

Toxicity of isolated Lantana (Lantana camara L) constituents to male and female guinea pigs.

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Ingia / Ingia

A toxin fraction was obtained from Lantana camara L (red variety) leaves by batch extraction and column chromatography on silica gel (60-120 mesh). The main constituents of the toxin preparation were lantadene A and lantadene B and it was devoid of reduced lantadene A. Oral administration (125 mg/kg

Biological action of lantadene C, a new hepatotoxicant from Lantana camara var. aculeata.

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Ingia / Ingia

Lantadene C (22 beta-2-methylbutanoyloxy-3-oxoolean-12-en-28-oic acid) isolated from the leaves of the hepatotoxic plant Lantana camara var. aculeata (Red) has been found to be identical with dihydrolantadene A reported earlier. Molecular structure of lantadene C has been deduced from single crystal

Detoxification of lantana hepatotoxin, lantadene A, using Alcaligenes faecalis.

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Ingia / Ingia

Detoxification of lantadene A (LA), the hepatotoxin from Lantana camara var. aculeata, by the bacterial strain Alcaligenes faecalis has been investigated. Lantadene A induced hepatotoxicity concomitant with increases in plasma bilirubin, blood plasma enzymes and histopathological lesions that typify

In vitro antioxidant activity potential of lantadene A, a pentacyclic triterpenoid of Lantana plants.

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Ingia / Ingia

Lantadenes are pentacyclic triterpenoids present in the leaves of the plant Lantana camara. In the present study, in vitro antioxidant activity and free radical scavenging capacity of lantadene A was evaluated using established in vitro models such as ferric reducing antioxidant power (FRAP),

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