ochronosis/glutathione

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NakalaMajaribio ya klinikiHati miliki

Chagua aina ya aina

4 matokeo

Redox-proteomics of the effects of homogentisic acid in an in vitro human serum model of alkaptonuric ochronosis.

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Ingia / Ingia

Alkaptonuria (AKU) is a rare inborn error of metabolism associated with a deficient activity of homogentisate 1,2-dioxygenase (HGO), an enzyme involved in tyrosine and phenylalanine metabolism. Such a deficiency leads to the accumulation of homogentisic acid (HGA) and its oxidized/polymerized

Homogentisic acid and structurally related compounds as intermediates in plasma soluble melanin formation and in tissue toxicities.

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Ingia / Ingia

Homogentisic acid (HGA) spontaneously starts to undergo oxidation and polymerization soon after the beginning of incubation in human blood or plasma at 37 degrees C, and forms plasma soluble melanins (PSM). Haemolysis accompanies this process in blood. The addition of equimolar quantities of

The toxicology of hydroquinone--relevance to occupational and environmental exposure.

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Ingia / Ingia

Hydroquinone (HQ) is a high-volume commodity chemical used as a reducing agent, antioxidant, polymerization inhibitor, and chemical intermediate. It is also used in over-the-counter (OTC) drugs as an ingredient in skin lighteners and is a natural ingredient in many plant-derived products, including

Hydroquinone and its analogues in dermatology - a potential health risk.

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Ingia / Ingia

Hydroquinone has been used for decades as a skin lightening agent. Since January 1, 2001, its use in cosmetics has been banned. This ban is as a result of mid-term effects such as leukoderma-en-confetti/occupational vitiligo and exogenous ochronosis. However, a recent literature search on

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Herbal & Natural Medicine

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