parathyroid neoplasms/albumin

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Expression, function, and regulation of the embryonic transcription factor TBX1 in parathyroid tumors.

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Ingia / Ingia

Transcription factors active in embryonic parathyroid cells can be maintained in adult parathyroids and be involved in tumorigenesis. TBX1, the candidate gene of 22q11.2-DiGeorge syndrome, which includes congenital hypoparathyroidism, is involved in parathyroid embryogenesis. The study aimed to

Tc-99m sestamibi localization of an ectopic mediastinal parathyroid tumor in a patient with primary hyperparathyroidism.

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Ingia / Ingia

A 50-year-old woman presented with pain and tenderness in the right flank. Urogram and ultrasound demonstrated the presence of an 8-mm calculus in the right kidney. There were persistently elevated serum calcium levels ranging from 10.7-11.4 mg/dL (normal range: 8.5-10.5) and borderline low serum

Cinacalcet hydrochloride relieves hypercalcemia in Japanese patients with parathyroid cancer and intractable primary hyperparathyroidism.

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Ingia / Ingia

Pharmacological treatment of hypercalcemia is essential for patients with parathyroid carcinoma and intractable primary hyperparathyroidism (PHPT). Use of the calcimimetic cinacalcet hydrochloride (cinacalcet) is an option to treat such patients. We investigated the efficacy and safety of cinacalcet

Correlations between vitamin D status and biochemical/clinical and pathological parameters in primary hyperparathyroidism.

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Ingia / Ingia

BACKGROUND To determine the prevalence of vitamin D deficiency and the effects of vitamin D status on parathyroid adenoma weight, clinical and biochemical indices in patients with primary hyperparathyroidism (pHPT) were studied. METHODS Eighty patients with pHPT who underwent surgical treatment and

An unusual cause of hypercalcemia in polycythemia vera: parathyroid adenoma.

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Ingia / Ingia

In this paper we describe a patient with polycythemia vera (PV), who presented with hypercalcemia due to a parathyroid adenoma. In November 1999, the patient was admitted to our hospital with meteorism and constipation. Her physical examination revealed plethora and hepatosplenomegaly. Laboratory

Excision efficiency of radioguided occult lesion localization in reoperative thyroid and parathyroid surgery.

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Ingia / Ingia

BACKGROUND The purpose of this study was to investigate the efficiency of a radioguided occult lesion localization technique in reoperative thyroid and parathyroid procedures in patients who had undergone previous neck exploration for thyroid or parathyroid disease. METHODS Twenty-one consecutive

Frequency of the calcium-sensing receptor variant A986S in patients with primary hyperparathyroidism.

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Ingia / Ingia

OBJECTIVE Recent studies have shown an influence of the calcium-sensing receptor variant A986S on the serum calcium concentration, suggesting that this genetic variant could be a candidate for various bone and mineral disorders. The intention of this study was therefore to investigate the frequency

Symptomatic Hypercalcemia in Patients with Primary Hyperparathyroidism Is Associated with Severity of Disease, Polypharmacy, and Comorbidity.

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Ingia / Ingia

Current primary hyperparathyroidism (PHPT) clinical presentation is asymptomatic in more than 90% of patients, while symptoms concern osteoporosis and rarely kidney stones. Here, we retrospectively investigated the prevalence of PHPT patients presenting with hypercalcemic-related symptoms (HS-PHPT)

Parathyroid Carcinoma: Diagnosis and Clinical Implications.

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Ingia / Ingia

Parathyroid carcinoma is a rare type of endocrine cancer, with significant morbidity and mortality associated with parathyroid hormone (PTH)-mediated hypercalcemia. Concerning clinical features for parathyroid cancer include severe hypercalcemia (albumin-corrected calcium > 3 mmol/L), a palpable

Clinical and histopathological characteristics of hyperparathyroidism-induced hypercalcemic crisis.

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Ingia / Ingia

BACKGROUND The clinical and pathological characteristics of hyperparathyroidism-induced hypercalcemic crisis (HIHC) are incompletely described. The present study was designed to elucidate the nature and effects of HIHC in patients undergoing parathyroidectomy in our unit. METHODS A prospective

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