8 matokeo
BACKGROUND
The role of allergen-specific CD4+ T lymphocytes in the pathophysiology of atopic disease is well established. Previous studies on allergen-specific T-cell responses have focused on the recognition of single major allergens to identify T-cell epitopes.
OBJECTIVE
However, it is not clear
With the approval of two grass tablets and one ragweed tablet for sublingual immunotherapy (SLIT) by the US FDA in April 2014, the practice of allergy immunotherapy (AIT) in the USA has dramatically changed. Until this time, there were no approved allergen extracts for sublingual administration and
BACKGROUND
The introduction of molecular diagnoses has provided evidence of the existence of several different allergenic profiles in grass-sensitised individuals, reflecting the large number of allergens involved. This methodology has become a potent tool for a correct diagnosis and for the
BACKGROUND
Grass pollen allergy is one of the most common allergies worldwide, and patients often show sensitization to an array of phylogenetically related species.
OBJECTIVE
To determine the effect of specific immunotherapy (SIT) with Phleum pratense extract on induction of the immune response to
Background: In allergology, the intradermal approach is generally used to establish an etiological diagnosis, with limited experience in specific allergen immunotherapy.
Objective:
BACKGROUND
IgE sensitization against grass pollen is a cause of seasonal allergic rhinitis.
OBJECTIVE
We sought to investigate the evolution at the molecular level and the preclinical predictive value of IgE responses against grass pollen.
METHODS
The German Multicentre Allergy Study examined a
BACKGROUND
Allergen immunotherapy has been shown to be an effective treatment for local allergic rhinitis (LAR) to house dust mites. Studies with pollen allergen immunotherapy are limited to observational studies. The aim of this study was to evaluate the clinical efficacy and safety of Phleum
BACKGROUND
Conventional diagnostic tests (such as radioallergosorbent test [RAST] and skin prick test [SPT]) use native raw pollen allergen extracts to establish allergy. However, recombinant allergens may offer important advantages compared with their natural counterparts.
OBJECTIVE
This study