podophyllotoxin/mtumbako

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NakalaMajaribio ya klinikiHati miliki

Chagua aina ya aina

2 matokeo

Aryltetralin lignans: chemistry, pharmacology and biotransformations.

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Ingia / Ingia

Podophyllotoxin derivatives like etoposide 7a, etophos 7b, and teniposide 7c are used clinically as potent chemotherapeutic agents for a variety of tumors including small cell lung carcinoma, testicular cancer, and malignant lymphoma. These compounds derived from a series of modifications which

Six enzymes from mayapple that complete the biosynthetic pathway to the etoposide aglycone.

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Ingia / Ingia

Podophyllotoxin is the natural product precursor of the chemotherapeutic etoposide, yet only part of its biosynthetic pathway is known. We used transcriptome mining in Podophyllum hexandrum (mayapple) to identify biosynthetic genes in the podophyllotoxin pathway. We selected 29 candidate genes to

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Herbal & Natural Medicine

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