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polyene/saratani

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15 matokeo
FIELD OF THE INVENTION This invention relates to carotenoid, retinoid and related conjugated polyene derivatives with cell-differentiation-inducing, anti-proliferative and anti-tumor properties, useful as chemotherapeutic and chemopreventive agents, and more particularly, to such derivatives

Polyene oxazoles and processes for their preparation

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
BACKGROUND OF THE INVENTION Polyketides are a diverse class of naturally occurring molecules typically produced by a variety of organisms, including fungi and mycelial bacteria, in particular actinomycetes. Although polyketides have widely divergent structures, they are classified together because

Polyene polyketides, processes for their production and their use as a pharmaceutical

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
FIELD OF INVENTION This invention relates to a new class of polyene polyketides, their pharmaceutically acceptable salts and derivatives, and to methods for their production. One method of obtaining these novel polyketides is by cultivation of novel strains of Streptomyces aizunensis; another method

Polyene polyketides, processes for their production and their use as a pharmaceutical

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
FIELD OF INVENTION This invention relates to a new class of polyene polyketides, their pharmaceutically acceptable salts and derivatives, and to methods for their production. One method of obtaining these novel polyketides is by cultivation of novel strains of Streptomyces aizunensis; another method
The invention relates to the field of medicine, oncology in particular, and can be used for chemotherapeutical treatment of oncological patients, suffering from different kinds of malignant neoplasms. Methods of treatment of cancer by means of chemical preparations are known. According to mechanism

Polyene compounds

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
DETAILED DESCRIPTION OF THE INVENTION The present invention pertains to compounds represented by the formula: ##SPC1## Wherein One adjacent pair of R.sub.1 through R.sub.5 is a trimethylene, tetramethylene, 1,3-butadienylene, oxytrimethylene or 3-oxypropenylene group which may be substituted with

Polyene compounds

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
SUMMARY OF INVENTION The present invention is concerned with novel polyene compounds, a process for their manufacture and pharmaceutical preparations which contain these polyene compounds. The polyene compounds provided by the present invention are compounds of the formula ##STR1## wherein R.sup.1

Polyene compounds

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
SUMMARY OF THE INVENTION This invention is directed to novel polyene compounds of the formula: ##STR1## wherein R.sub.1 and R.sub.2 each are hydrogen, halogen or lower alkoxy; R.sub.3, R.sub.4, R.sub.5 and R.sub.6 each are hydrogen or lower alkyl; R.sub.7 is hydroxymethyl, lower alkoxymethyl, lower

Retinal cyclodextrin acetals and hemiacetals for treating skin complexion disorder

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
BACKGROUND OF THE INVENTION The enhancement of physical appearance occupies greater focus in human life than nearly all other daily life-related actions. There are far more consumer products available for the beautification of human body than for the treatment of human ailments. The improvement of

Chirally correct retinal cyclodextrin hemiacetals for clarifying skin complexion

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
BACKGROUND OF THE INVENTION The enhancement of physical appearance occupies greater focus in human life than nearly all other daily life-related actions. There are far more consumer products available for the beautification of human body than for the treatment of human ailments. The improvement of

Chirally correct retinal cyclodextrin hemiacetals for clarifying skin complexion

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
BACKGROUND OF THE INVENTION The enhancement of physical appearance occupies greater focus in human life than nearly all other daily life-related actions. There are far more consumer products available for the beautification of human body than for the treatment of human ailments. The improvement of

Water-soluble AIE luminogens for monitoring and retardation of fibrillation of amyloid proteins

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
TECHNICAL FIELD The presently described subject matter relates generally to compounds that exhibit aggregation induced emission (AIE), and more particularly to water-soluble conjugated polyene compounds that exhibit aggregation induced emission. The conjugated polyene compounds can be used as

Water-soluble AIE luminogen for monitoring and retardation of amyloid fibrillation of insulin

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
FIELD OF THE INVENTION The presently described subject matter relates generally to compounds that exhibit aggregation induced emission, and more particularly to water-soluble conjugated polyene compounds that exhibit aggregation induced emission. The conjugated polyene compounds can be used as

Antitumoral method by administration of partricin derivatives

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
Partricin, a mixture of partricin A and partricin B (The Merck Index XII Ed., no. 7181), is a polyene substance obtained through fermentation of a special S. aureofaciens strain, and exhibiting very high antifungal activity. Since the substance as such is rather toxic to be used in therapy, several

Antitumoral method by administration of partricin derivatives

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
Partricin, a mixture of partricin A and partricin B (The Merck Index XII Ed., no. 7181), is a polyene substance obtained through fermentation of a special S. aureofaciens strain, and exhibiting very high antifungal activity. Since the substance as such is rather toxic to be used in therapy, several
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