3 matokeo
A new prenylcoumarin, 5-methoxyl-4,2'-epoxy-3-(4', 5'-dihydroxyphenyl)-linear pyranocoumarin (1), and a new flavonoid, 3-acetyl-3,5,4'-trihydroxy-7-methoxylflavone (2), were isolated from the roots of Ficus hirta. Their structures were elucidated by spectroscopic methods including 1D-, 2D- NMR and
Bioassay-guided fractionation of the active AcOEt-soluble layer led to the isolation of two new pyranocoumarins, 3-hydroxyxanthyletin (1) and 3-methoxyxanthyletin (2), along with 22 known compounds including four simple coumarins, i.e., xanthyletin (3), umbelliferone (4), scopoletin (5), and
Fruits of Ficus carica cultivar Dottato from Italy were examined to assess how the stage of ripeness influences their chemical composition, antioxidant activity, pancreatic lipase inhibition and antiproliferative properties on C32 melanoma cells. Fruits of the first harvest (June) showed a major