rectal prolapse/protease

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NakalaMajaribio ya klinikiHati miliki

Chagua aina ya aina

3 matokeo

Skin wound healing in MMP2-deficient and MMP2 / plasminogen double-deficient mice.

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Ingia / Ingia

During healing of incisional skin wounds, migrating keratinocytes dissect their way under the crust to re-epithelialize the wounded area. The efficiency of this tissue remodelling process depends on the concomitant activity of several extracellular proteases, including members of the plasminogen

Loss of fibrinogen rescues mice from the pleiotropic effects of plasminogen deficiency.

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Ingia / Ingia

Plasmin(ogen) is an extracellular serine protease implicated in the activation of latent growth factors and procollagenase, degradation of extracellular matrix components, and fibrin clearance. Plasminogen (Plg) deficiency in mice results in high mortality, wasting, spontaneous gastrointestinal

Failure of pelvic organ support in mice deficient in fibulin-3.

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Ingia / Ingia

Fibulin-5 is crucial for normal elastic fiber synthesis in the vaginal wall; more than 90% of fibulin-5-knockout mice develop pelvic organ prolapse by 20 weeks of age. In contrast, fibulin-1 and -2 deficiencies do not result in similar pathologies, and fibulin-4-knockout mice die shortly after

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Herbal & Natural Medicine

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