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rheum/protease

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NakalaMajaribio ya klinikiHati miliki
3 matokeo

Anti-SARS coronavirus 3C-like protease effects of Rheum palmatum L. extracts.

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Ingia / Ingia
The present study aims to clarify the inhibitive effect of the compounds from Rheum palmatum L. on the SARS-3CL protease. The SARS-CoV 3CL gene was amplified from RNA of the SARS virus by PCR. The SARS-CoV 3CL protease was purified from a colon bacillus recombinant. Drugs and 3CL protease were

Link peptide cartilage growth factor is degraded by membrane proteinases.

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Ingia / Ingia
The peptide DHLSDNYTLDHDRAIH (Link N), cleaved from the N-terminus of the link protein component of cartilage proteoglycan aggregates by the action of stromelysin, can act as a growth factor and stimulate synthesis of proteoglycans and collagen in articular cartilage [McKenna, Liu, Sansom and Dean

Emodin inhibits TNF alpha-induced MMP-1 expression through suppression of activator protein-1 (AP-1).

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Ingia / Ingia
Matrix metalloproteinases (MMPs) are the proteases involved in the degradation of the extracellular matrix. MMP-1 is thought to be one of the key enzymes acting in fibrolysis, a process closely related to tissue remodeling. In this study, we found that emodin, an anthraquinone which has been
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