robin/inflammation

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Inflammatory proteins and the severity of dilated Virchow-Robin Spaces in the elderly.

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Ingia / Ingia

Recent studies suggest dilated Virchow-Robin Spaces (dVRS) could be a manifestation of cerebral small-vessel disease, but little is known about their risk factors. As inflammation has been associated with other brain MRI findings, we investigated whether interleukin-6 and C-reactive protein were

Basement membrane proteins in multiple sclerosis-associated inflammatory cuffs: potential role in influx and transport of leukocytes.

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Ingia / Ingia

Perivascular accumulation of macrophages and lymphocytes is a prominent feature of multiple sclerosis (MS) pathology. To enter the brain parenchyma, immune cells need to migrate across the blood-brain barrier through a number of well-defined processes. So far, little attention has been given to the

Cerebrospinal fluid diversion in patients with enlarged Virchow-Robin spaces without ventriculomegaly.

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Ingia / Ingia

OBJECTIVE Enlarged Virchow-Robin spaces (eVRS) are an MRI biomarker in several neurological diseases of inflammatory, neurodegenerative, vascular, metabolic, or genetic origin. We report on a further condition in which eVRS were observed in patients with an ongoing chronic hydrocephalus-like

Virchow-Robin spaces on magnetic resonance images of children with adrenoleukodystrophy.

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Ingia / Ingia

BACKGROUND Perivascular spaces of the brain, also known as Virchow-Robin spaces (VRS), are of immunological and neuropathological relevance and can be observed in magnetic resonance images (MRI). Their histopathological significance in X-linked adrenoleukodystrophy (ALD) has been reported. Aim of

Dilated Virchow-Robin spaces in cryptococcal meningitis associated with AIDS: CT and MR findings.

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Ingia / Ingia

We present two patients with AIDS complicated by cryptococcal meningitis who displayed focal hypodense nonenhancing lesions in CT in the basal ganglia with corresponding areas of increased T2 and decreased T1 signal on magnetic resonance (MR). These lesions corresponded precisely to the distribution

Sandlike appearance of Virchow-Robin spaces in early multiple sclerosis: a novel neuroradiologic marker.

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Ingia / Ingia

OBJECTIVE The distinctive hyperintensity of multiple sclerosis (MS) lesions on T2-weighted brain MR images is well recognized. However, Virchow-Robin spaces (VRSs), especially in early MS, have not been described. Our purpose was to determine the frequency of VRSs in recent-onset MS. METHODS Brain

Leptomeningeal and adventitial gliosis as a consequence of chronic inflammation.

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Ingia / Ingia

Astroglial cell bodies and processes identified ultrastructurally and immunocytochemically are described within the subarachnoid and Virchow-Robin spaces of white matter throughout the CNS of Strain 13 guinea-pigs with chronic relapsing experimental allergic encephalomyelitis. These heterotopic

Dilated Virchow-Robin spaces and multiple sclerosis: 3 T magnetic resonance study.

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Ingia / Ingia

OBJECTIVE The aim of this study was to assess differences in the presence, size, number and site of dilated cerebral Virchow-Robin spaces (VRSd) between patients with multiple sclerosis (MS) in the inactive phase and healthy controls, and between MS patients with disabling (MSd) or nondisabling

Enlarged Virchow Robin spaces associate with cognitive decline in multiple sclerosis.

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Ingia / Ingia

The clinical significance of Virchow Robin spaces (VRS) in inflammatory brain disorders, especially in multiple sclerosis (MS), is still undefined. We analysed enlarged VRS (eVRS) by means of phase sensitive inversion recovery (PSIR) MRI sequence and investigated their association with inflammation

Features of Virchow-Robin spaces in newly diagnosed multiple sclerosis patients.

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Ingia / Ingia

BACKGROUND Virchow-Robin spaces (VRSs) are perivascular pia-lined extensions of the subarachnoid space around the arteries and veins as they enter the brain parenchyma. These spaces are responsible for inflammatory processes within the brain. OBJECTIVE This study was designed to shed more light on

Validation of weak biological effects by round robin experiments: cytotoxicity/biocompatibility of SiO2 and polymer nanoparticles in HepG2 cells.

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Ingia / Ingia

All over the world, different types of nanomaterials with a diversified spectrum of applications are designed and developed, especially in the field of nanomedicine. The great variety of nanoparticles (NPs), in vitro test systems and cell lines led to a vast amount of publications with conflicting

[Onychoheterotopia with polyonychia associated with Pierre Robin syndrome: apropos of a new case. (Trial of classifying nail ectopia)].

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Ingia / Ingia

The authors report the second case in the English language literature of a rare abnormality of the fingers and nails associated with Pierre Robin syndrome. The patient was born at term to non-consanguineous parents. The only potentially toxic drug taken by the mother during the first months of

Do Nonsteroidal Anti-Inflammatory Drugs Have a Deleterious Effect on Cartilage Repair? A Systematic Review.

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Ingia / Ingia

The purpose of this study was to systematically review the available evidence regarding any plausible deleterious effects of nonsteroidal anti-inflammatory drugs (NSAIDs) on chondrocytes, chondrocyte differentiation, and allograft or autograft incorporation after cartilage repair

Non-Steroidal Anti-Inflammatory Drugs and the Risk of Pneumonia Complications: A Systematic Review

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Ingia / Ingia

There have been concerns regarding the safety of non-steroidal anti-inflammatory drugs (NSAIDs) in patients with respiratory infections. However, to date the quality of the evidence has not been systematically assessed. The purpose of this systematic review was to evaluate the role of NSAIDs on

Perivascular spaces--MRI marker of inflammatory activity in the brain?

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Ingia / Ingia

The Virchow-Robin spaces (VRS), perivascular compartments surrounding small blood vessels as they penetrate the brain parenchyma, are increasingly recognized for their role in leucocyte trafficking as well as for their potential to modulate immune responses. In the present study, we investigated VRS

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