ruscogenin/ruscus

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High-throughput LC/MS/MS analysis of ruscogenin and neoruscogenin in Ruscus aculeatus L.

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Ingia / Ingia

A new, sensitive LC/MS/MS method was developed for the quantification of ruscogenin and neoruscogenin in hydrolyzed extracts from Ruscus aculeatus L. (Liliaceae). The two sapogenins were separated on a Zorbax SB-C18 column under isocratic conditions. The detection was performed in the multiple

Quantitative determination of ruscogenin in Ruscus species by densitometric thin-layer chromatography.

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Ingia / Ingia

A densitometric t.l.c. method of quantitative determination of ruscogenin was elaborated. After separation with the aid of t.l.c., the colourless ruscogenin spots were located with the aid of a p-dimethyl-aminobenzaldehyde solution and were submitted to densitometry. It was found that under the

Biotechnological production of ruscogenins in plant cell and organ cultures of Ruscus aculeatus.

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Ingia / Ingia

Ruscus aculeatus is a threatened medicinal plant whose main bioactive components, the ruscogenins, have long been used in the treatment of hemorrhoids and varicose veins, but recently demonstrated activity against some types of cancer. Plant cell biofactories could constitute an alternative to the

Ex situ conservation of Ruscus aculeatus L. - ruscogenin biosynthesis, genome-size stability and propagation traits of tissue-cultured clones.

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Ingia / Ingia

Ruscus aculeatus L. is a perennial semi-shrub with distinctive leaf-like branches (cladodes). Rhizomes and roots contain steroidal saponins (ruscogenins) that are used in medicine and cosmetics for their anti-inflammatory, venotonic and antihaemorroidal activity. Problematic cultivation of the

HPTLC densitometric determination of ruscogenins in dry extract of Ruscus aculeatus L.

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Ingia / Ingia

[On the problem of isolation of ruscogenin from Ruscus hyrcanus G. Woron].

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Ingia / Ingia

Ruscus Genus: A Rich Source of Bioactive Steroidal Saponins.

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Ingia / Ingia

The genus Ruscus (Asparagaceae family) is native to the Mediterranean, Southern and Western Europe and is represented by perennial, rhizomatous, and evergreen shrubs. Among the approximately seven species spread throughout Europe up to Iran, Ruscus aculeatus L. (butcher's broom) is the most widely

Steroidal saponins from the underground parts of Ruscus aculeatus and their cytostatic activity on HL-60 cells.

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Ingia / Ingia

Phytochemical examination of the underground parts of Ruscus aculeatus has been undertaken as part of systematic study of plants of the Liliaceae. Six new spirostanol saponins and five new furostanol saponins were isolated, and their structures were assigned on the basis of spectroscopic analysis,

Bone protective effects of purified extract from Ruscus aculeatus on ovariectomy-induced osteoporosis in rats.

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Ingia / Ingia

Ruscus aculeatus is a source of steroidal saponins that could mimic sex hormones and could help alleviate the risk of fracture in osteoporotic patients. The aim of the present study was to evaluate the in vitro effects of an extract from R. aculeatus (ERA) on the proliferation of human

Ruscus aculeatus (butcher's broom) as a potential treatment for orthostatic hypotension, with a case report.

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Ingia / Ingia

BACKGROUND Chronic orthostatic hypotension (OH) is frequently a severely debilitating disease that affects large groups of the population with autonomic insufficiency--the elderly; patients with diabetes, Parkinson's disease, and chronic fatigue syndrome; and anyone on drugs that affect the

Anti-elastase and anti-hyaluronidase activities of saponins and sapogenins from Hedera helix, Aesculus hippocastanum, and Ruscus aculeatus: factors contributing to their efficacy in the treatment of venous insufficiency.

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Ingia / Ingia

Triterpene and steroid saponins and sapogenins of medicinal plants (Aesculus hippocastanum L., Hedera helix L., Ruscus aculeatus L.) are claimed to be effective for the treatment/prevention of venous insufficiency. In this work we evaluated the inhibitory effects of these plant constituents on the

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