saururus cernuus/catalepsy

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Preliminary evaluation of manassantin A, a potential neuroleptic agent from Saururus cernuus.

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Ingia / Ingia

Manassantin A (MNS-A), a novel dineolignan isolated from Saururus cernuus was evaluated for its central depressant effects. Intraperitoneal (IP) administration of MNS-A to mice at nontoxic doses caused a decrease in spontaneous motor activity and inhibition of amphetamine-induced stereotypy, with an

Further studies on the neuroleptic profile of manassantin A.

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Ingia / Ingia

In an earlier preliminary study, manassantin A, a neolignoid from Saururus cernuus was found to show neuroleptic type activity in mice when given by the i.p. route. It blocked the stereotypy and hyperactivity caused by amphetamine at doses comparable to those of haloperidol, but unlike the latter,

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Herbal & Natural Medicine

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