seneciphylline/senecio

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Senecionine, Seneciphylline, Jacobine and Otosenine from Senecio cineraria.

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Ingia / Ingia

[ABOVE-GROUND PARTICLES OF SENECIO AS A SOURCE FOR OBTAINING ALKALOIDS OF PLATYPHILLINE, SARRACENINE AND SENECIPHYLLINE].

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Ingia / Ingia

Alkaloids from Senecio aegyptius and S. desfontainei.

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Ingia / Ingia

Otosenine and senecionine/seneciphyllme were isolated from Senecio aegyptius and S. desfontainei, respectively. Senecionine and seneciphylline easily cocrystallize; m.p. and IR-spectra of mixtures of both alkaloids and their separation by PC are described. IR evidence of individual alkaloids and of

Microsomal metabolism of pyrrolizidine alkaloids from Senecio jacobaea. Isolation and quantification of 6,7-dihydro-7-hydroxy-1-hydroxymethyl-5H-pyrrolizine and N-oxides by high performance liquid chromatography.

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Ingia / Ingia

The metabolism in vitro of four pyrrolizidine alkaloids from the poisonous plant Senecio jacobaea was studied. The pyrrolizidine alkaloids jacobine, jacoline, senecionine, and seneciphylline, all macrocyclic diesters of retronecine, were incubated with rat liver microsomes. Analysis of incubation

Influence of grass pellet production on pyrrolizidine alkaloids occurring in Senecio aquaticus-infested grassland.

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Ingia / Ingia

1,2-Dehydro-pyrrolizidine alkaloids (PA) and their N-oxides (PANO) exhibit acute and chronic toxic effects on the liver and other organs and therefore are a hazard for animal and human health. In certain regions of Germany, an increasing spread of Senecio spp. (ragwort) on grassland and farmland

Comparison of the toxicities of Senecio jacobaea, Senecio vulgaris and Senecio glabellus in rats.

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Ingia / Ingia

The toxicity of Senecio jacobaea, S. vulgaris and S. glabellus to rats was assessed in a feeding trial. The plants were of similar toxicity, with a plant dry matter intake of about 20% of initial body weight being a lethal dose. Gas chromatography-mass spectrometry analysis demonstrated the presence

Determination of pyrrolizidine alkaloids in honey from selected sites by solid phase extraction and HPLC-MS.

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Ingia / Ingia

A method was developed for the determination in honey of the Ragwort (Senecio jacobaea) derived pyrrolizidine alkaloids jacoline, jacozine, jacobine, seneciphylline and senecionine, combining solid-phase extraction with high performance liquid chromatography and atmospheric pressure chemical

Metabolism of pyrrolizidine alkaloids by Peptostreptococcus heliotrinreducens and a mixed culture derived from ovine ruminal fluid.

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Ingia / Ingia

A mixed culture of ovine ruminal microbes metabolizes the macrocyclic pyrrolizidine alkaloids present in the plant Senecio jacobaea, including jacobine and seneciphylline. Previous attempts to identify metabolites of these alkaloids have not been successful. The objective of this study was to

Toxicity of pyrrolizidine alkaloids to Spodoptera exigua using insect cell lines and injection bioassays.

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Ingia / Ingia

Pyrrolizidine alkaloids (PAs) are feeding deterrents and toxic compounds to generalist herbivores. Among the PAs of Jacobaea vulgaris Gaertn, jacobine and erucifoline are the most effective against insect herbivores as indicated by correlative studies. Because little is known about the effect of

Alkaloids from Senecio aquaticus.

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Ingia / Ingia

Erucifoline (1) and 9-angeloylhastanecine (2) were isolated from the aerial parts of Senecio aquaticus. Five other pyrrolizidine alkaloids were tentatively identified by GC/MS analysis: jacobine; seneciphylline; spartioidine; jacozine; and senecionine.

Hydrolysis rates of pyrrolizidine alkaloids derived from Senecio jacobaea.

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Ingia / Ingia

Many of the commonly studied pyrrolizidine alkaloids (PAs) are built upon the subgroup retronecine (RET), which is released from the parent molecule by either base catalyzed or enzymatic hydrolysis of the ester linkages. The rate of appearance of RET in a hydrolytic study would thus reflect the rate

Pyrrolizidine alkaloids: their occurrence in honey from tansy ragwort (Senecio jacobaea L.)

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Ingia / Ingia

The hepatotoxic alkaloids known to occur in tansy ragwort (Senecio jacobaea L.) are also present in honey produced from the nectar of this species. These alkaloids, which inclued senecionine, seneciphylline, jacoline, jaconine, jacobine, and jacozine, are potentially carcinogenic, mutagenic, and

Identification of five hepatotoxic pyrrolizidine alkaloids in a commonly used traditional Chinese medicinal herb, Herba Senecionis scandentis (Qianliguang).

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Ingia / Ingia

Senecio scandens Buch.-Ham is a plant source for a commonly used traditional Chinese medicinal (TCM) herb Qianliguang. A TCM herbal proprietary product containing Qianliguang as the major herb for the treatment of sinusitis has been used in China for several decades, and has also been exported to

Pyrrolizidine alkaloids in pollen and pollen products.

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Ingia / Ingia

Recently, 1,2-dehydropyrrolizidine alkaloid (PA) ester alkaloids, found predominantly as their N-oxides (PANOs, pyrrolizidine N-oxides), have been reported in both honey and in pollen obtained directly from PA plants and pollen loads collected by bees, raising the possibility of health risks for

Pyrrolizidine alkaloid level in Senecio bicolor (Wilid.) Tod, ssp. cineraria (DC.) from middle Europe.

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Ingia / Ingia

From Senecio bicolor, ssp. cineraria, cultivated in middle Europe, seven pyrrolizidine alkaloids (PA) were isolated and their structures elucidated by spectroscopical methods. Besides the already known senecionine, integerrimine, seneciphylline, jacobine, jacoline and jaconine the jacobine-acetate

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