taxus cuspidata/tyrosine

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NakalaMajaribio ya klinikiHati miliki

Chagua aina ya aina

2 matokeo

Cloning, heterologous expression, and characterization of a phenylalanine aminomutase involved in Taxol biosynthesis.

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Ingia / Ingia

Biosynthesis of the N-benzoyl phenylisoserinoyl side chain of the anticancer drug Taxol starts with the conversion of 2S-alpha-phenylalanine to 3R-beta-phenylalanine by phenylalanine aminomutase (PAM). A gene cloning approach was based on the assumption that PAM would resemble the well known plant

Stereochemical aspects of the biosynthesis of the epimeric cyanogenic glucosides dhurrin and taxiphyllin.

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Ingia / Ingia

Dhurrin, I ((S)-p-hydroxymandelonitrile-beta-D-glucopyranoside), and taxiphyllin, II (the (R) epimer), occur in the genera Sorghum and Taxus, respectively. Both derive biosynthetically from L-tyrosine via the hydroxylation of p-hydroxyphenylacetonitrile, III. (3R)- and (3S)-L-[3-3H1]tyrosine,

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Herbal & Natural Medicine

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