A stable composition and method for cutaneous therapy, particularly for treatment of acne, dermatophyte infection, poison ivy reactions and body odor development. The composition includes benzoyl peroxide particles, water and a solvent for benzoyl peroxide which has a boiling point substantially greater than 100.degree. C. Evaporation of the water leaves a solvent-benzoyl peroxide solution particularly non-irritative and effective in activity against cutaneously abiding microorganisms and contactants characteristic of certain plants.

Board of Regents, The University of Texas System

Therapeutic compositions containing benzoyl peroxide

The present invention is a method of treating mammals for alleviating inflammation by utilization of a non-steroid topical agent. The agent is ethyl linoleate [ethyl-cis,cis(9,12)-octadecadienoate] which may be combined in a preferred formulation with one or more antioxidants such as .alpha.-tocopherol, d,l-histidine, and tertiary butyl hydroquinone; a stabilizer such as Tween-80; and inert esters such as ethyl oleate, ethyl palmitate, and ethyl stearate. The agent is applied in a therapeutic dosage range of 0.2-0.8 mg/cm.sup.2 of body surface both internal and external, with a preferred dosage of 0.5 mg/cm.sup.2. This topical remedy for inflammation for internal and external body surfaces is utilized principally in a single dose but may be utilized in multiple doses are required due to low toxicity (60:1). Among the conditions with inflammatory responses amenable to treatment are ultraviolet ratiation, solar radiation, non-infectious conjunctivitis, hemorrhoids (acute), abrasions, ingrown finger or toenail (granulation), skin graft donor sites, vaginitis, poison ivy, psoriasis, herpes simplex (cold sores, aphthous ulcers), pruritis ani/cruri, chemical inflammation, and insect stings/bites.

toxicodendron succedaneum/antifungal

Therapeutic compositions containing benzoyl peroxide

Therapeutic compositions containing benzoyl peroxide

Non-steroid topical agent for alleviating inflammation in mammals

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