Effects of Expiratory Pressure on Arterial Oxygenation During Hypoxia
Anahtar kelimeler
Öz
Açıklama
Two types of procedures will be tested in a random order, interspaced by resting periods : threshold PEEP set at 5,10 and 15 cm of water and pursed leap breathing.
Subjects will be tested at rest, and during light exercise (30% of sea level predicted VO2max).
FiO2 will be set at 12.5% (4000 m). fc, VE, PETCO2, TA, ECG, cardiac output, and tissular oxygenation will be monitored.
Tarih
| Son Doğrulandı: | 01/31/2012 |
| İlk Gönderilen: | 12/13/2010 |
| Tahmini Kayıt Gönderildi: | 12/13/2010 |
| İlk Gönderilen: | 12/14/2010 |
| Son Güncelleme Gönderildi: | 02/26/2012 |
| Son Güncelleme Gönderildi: | 02/27/2012 |
| Fiili Çalışma Başlangıç Tarihi: | 01/31/2011 |
Durum veya hastalık
Müdahale / tedavi
Device: healthy active subjects
Evre
Kol Grupları
| Kol | Müdahale / tedavi |
|---|---|
| healthy active subjects with and without high altitude intolerance | Device: healthy active subjects Various set of pressures : 0, 5, 10 cm H20; pursed lips breathing |
Uygunluk kriterleri
| Çalışmaya Uygun Yaşlar | 18 Years İçin 18 Years |
| Çalışmaya Uygun Cinsiyetler | Female |
| Örnekleme yöntemi | Non-Probability Sample |
| Sağlıklı Gönüllüleri Kabul Ediyor | Evet |
| Kriterler | Inclusion Criteria : - active (> 2 hrs/week physical activity) - adult - non smoking volunteers Exclusion Criteria : - cardiac, respiratory, neuromuscular, metabolic pathology |
Sonuç
Birincil Sonuç Ölçütleri
1. SpO2 [mean over 1 minute]
İkincil Sonuç Ölçütleri
1. peripheral HbO2/DeoxyHb [1 min]
2. cardiac output [mean over 1 min]
3. pattern of breathing (fR, VT, PETCO2) [1 min]
