Diagnostic Contribution of Ultrasonography in Breast Cancer-Related Lymphedema
Anahtar kelimeler
Öz
Açıklama
Patients with unilateral breast cancer-related lymphedema will be included in the study. The circumferences will be measured with a measuring tape from wrist ulnar styloid to axilla at 4 cm intervals. The point where the difference between the upper extremities was highest and the control point with no difference in the lower extremities will be marked. Ultrasonographic skin and subcutaneous thickness measurements will be performed from 4 quadrants; volar medial-lateral and dorsal medial-lateral sides of the extremity, with the probe placed transverse and perpendicular to the skin at the marked points.
The severity of lymphedema was graded ultrasonographically according to the SEG scale. (Stage 0: No increase in echogenicity in the subcutaneous layer. That is, subcutaneous fat is observed as black. Stage 1: Diffuse increase in echogenicity, but identifiable horizontal or oblique-oriented echogenic lines caused by bundles of connective tissue can be seen. Stage 2: A widespread increase in echogenicity echogenic lines cannot be identified.) Spearman test was used for correlations and Receiver Operating Characteristics (ROC) curve analysis was used to estimate the diagnostic accuracy. Sensitivity and specificity were calculated using a statistically significant threshold. Differences between ultrasonographic measurements between control points in lower extremities were compared with Wilcoxon test.
The minimum number of patients to be included in the study, according to the G-Power program, effect size d = 0.5, alpha-α = 0.05 and power 0.80 was calculated to be at least 34.
Tarih
Son Doğrulandı: | 04/30/2020 |
İlk Gönderilen: | 12/23/2019 |
Tahmini Kayıt Gönderildi: | 12/26/2019 |
İlk Gönderilen: | 12/29/2019 |
Son Güncelleme Gönderildi: | 05/19/2020 |
Son Güncelleme Gönderildi: | 05/20/2020 |
Fiili Çalışma Başlangıç Tarihi: | 01/01/2020 |
Tahmini Birincil Tamamlanma Tarihi: | 01/30/2020 |
Tahmini Çalışma Tamamlanma Tarihi: | 01/30/2020 |
Durum veya hastalık
Müdahale / tedavi
Diagnostic Test: measure
Evre
Kol Grupları
Kol | Müdahale / tedavi |
---|---|
Other: measure circumference measure, ultrasonographic measure | Diagnostic Test: measure ultrasonographic measurement- Subcutaneous ultrasound echogenicity (SEG) and Skin and subcutaneous thickness measurement |
Uygunluk kriterleri
Çalışmaya Uygun Yaşlar | 18 Years İçin 18 Years |
Çalışmaya Uygun Cinsiyetler | Female |
Sağlıklı Gönüllüleri Kabul Ediyor | Evet |
Kriterler | Inclusion Criteria: 1. To be diagnosed with breast cancer-related unilateral lymphedema 2. Being over 18 years old 3. Having a female gender Exclusion Criteria: 1. Bilateral breast cancer 2. Existing upper extremity infection 3. Lymphangitis 4. Refusal to participate in the study 5. Presence of edema in lower extremity |
Sonuç
Birincil Sonuç Ölçütleri
1. ultrasonographic measurement [baseline]