Journal of Asian Natural Products Research 2014-Oct
Anti-inflammatory amide alkaloids from the stems of Clausena emarginata.
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Two new amide alkaloids, clauemaramide A (1) and clauemaramide B (2), and three known analogs were isolated from the stems of Clausena emarginata. Their structures were determined on the basis of spectroscopic analyses. The absolute configurations of 1 and 2 were confirmed by CD spectroscopy. Compound 3 showed moderate inhibitory effects on LPS-induced NO production (IC₅₉ value = 4.9 μM).
